Department of Gastroenterology, Western General Hospital, The Univesity of Edinburgh, Crewe Road South, Edinburgh EH4 2XU, UK.
Department of Social Sciences, Clinical and Health Psychology, University of Nicosia, P.O. Box 24005, CY-1700, Cyprus.
Br Med Bull. 2021 Jun 10;138(1):16-28. doi: 10.1093/bmb/ldab010.
Both depression and anxiety are identified as significant experiences in inflammatory bowel disease (IBD); whether these are a consequence of the disease or an active contributor to the disease remains controversial. This review aimed to identify and critique recent evidence regarding mental health in IBD.
PubmedⓇ, OvidⓇ, EmbaseⓇ, EBSCO PsychInfo and Google-Scholar were searched within the last 5 years (2016-2020).
Overall, both depression and anxiety affect disease activity, relapse and healthcare utilization.
There is some controversy on whether depression and anxiety affect IBD outcomes differently depending on IBD subtype.
The data support the need for depression and anxiety assessment to be incorporated in the routine management of IBD patients; prompt psychiatric and psychological management may ultimately reduce disease activity, relapses and healthcare costs.
More longitudinal research may further enlighten the role of depression and anxiety in IBD. Similarly, randomized controlled trials to investigate and clarify the effect of psychiatric/psychological management on IBD outcomes.
抑郁和焦虑均被确定为炎症性肠病（IBD）患者的重要经历；这些情况是疾病的结果还是疾病的主要诱因仍存在争议。本综述旨在确定并评价最近关于 IBD 患者心理健康的证据。
在过去 5 年（2016-2020 年）内，检索了 Pubmed Ⓡ、Ovid Ⓡ、Embase Ⓡ、EBSCO PsychInfo 和 Google-Scholar。
总体而言，抑郁和焦虑均影响疾病活动、复发和医疗保健利用。
抑郁和焦虑是否根据 IBD 亚型的不同而对 IBD 结局产生不同影响，目前尚存争议。
数据支持将抑郁和焦虑评估纳入 IBD 患者常规管理的必要性；及时的精神科和心理科管理最终可能会降低疾病活动度、复发率和医疗保健费用。
更多的纵向研究可能会进一步阐明抑郁和焦虑在 IBD 中的作用。同样，需要开展随机对照试验来研究和阐明精神科/心理科管理对 IBD 结局的影响。
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