Bernabeu Purificación, Belén-Galipienso Olivia, van-der Hofstadt Carlos, Gutiérrez Ana, Madero-Velázquez Lucía, García Del Castillo Gloria, García-Sepulcre Mariana-Fe, Aguas Mariam, Zapater Pedro, Rodríguez-Marín Jesús, Ruiz-Cantero María-Teresa, Cameo José I, Jover Rodrigo, Sempere Laura
Health Psychology Department, Dr. Balmis General University Hospital, Alicante Institute for Health and Biomedical Research (ISABIAL), Alicante, Spain.
Gastroenterology Department, Dr. Balmis General University Hospital, Alicante Institute for Health and Biomedical Research (ISABIAL), Alicante, Spain.
Front Psychol. 2024 Jan 29;15:1334308. doi: 10.3389/fpsyg.2024.1334308. eCollection 2024.
Psychological factors, such as stress, anxiety, and depression, are frequently related to inflammatory bowel disease (IBD). However, few studies have examined these factors in patients newly diagnosed with IBD. The aim of the present study was to test the psychological burden in patients with a recent diagnosis of IBD and the factors related to this psychological burden.
We performed a prospective, multi-center, observational study in patients with a new diagnosis of IBD (≤6 months). The patients were recruited from four different Spanish hospitals. Clinical and demographic characteristics were collected. Patients were evaluated using the Hospital Anxiety and Depression Scale and quality of life questionnaire for patients with inflammatory bowel disease (IBDQ-32). The Scale of Stress Perceived by the Disease was used to assess stressful life events.
We included 156 patients newly diagnosed with IBD [69 women; 80 Crohn's disease (CD) and 76 ulcerative colitis (UC)], with a mean age of 42.3 (SD 16.21) years. A total of 37.2% of patients had symptoms of anxiety and 17.3% had symptoms of depression. Quality of life was affected in 30.1% of patients. Factors related to anxiety in early IBD were being a woman and having CD. The only factor related to depression was the presence of comorbidity. Being a woman and having suffered previous stressful life events were factors related to impaired quality of life.
Anxiety, depression, and impaired quality of life are frequent in patients with a recent diagnosis of IBD. This psychological burden is greater in women.
心理因素，如压力、焦虑和抑郁，常与炎症性肠病（IBD）相关。然而，很少有研究在新诊断为IBD的患者中考察这些因素。本研究的目的是测试近期诊断为IBD的患者的心理负担以及与这种心理负担相关的因素。
我们对新诊断为IBD（≤6个月）的患者进行了一项前瞻性、多中心观察性研究。患者从西班牙四家不同的医院招募。收集临床和人口统计学特征。使用医院焦虑抑郁量表和炎症性肠病患者生活质量问卷（IBDQ-32）对患者进行评估。使用疾病感知压力量表评估应激性生活事件。
我们纳入了156例新诊断为IBD的患者[69名女性；80例克罗恩病（CD）和76例溃疡性结肠炎（UC）]，平均年龄为42.3（标准差16.21）岁。共有37.2%的患者有焦虑症状，17.3%的患者有抑郁症状。30.1%的患者生活质量受到影响。IBD早期与焦虑相关的因素是女性和患有CD。与抑郁相关的唯一因素是合并症的存在。女性和既往经历过应激性生活事件是与生活质量受损相关的因素。
近期诊断为IBD的患者中焦虑、抑郁和生活质量受损很常见。这种心理负担在女性中更重。
