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与后路初次全髋关节置换相比,直接前入路具有短期功能获益和更高的资源需求:功能结局和成本的荟萃分析。

Direct anterior approach has short-term functional benefit and higher resource requirements compared with the posterior approach in primary total hip arthroplasty : a meta-analysis of functional outcomes and cost.

机构信息

Resident Research Partnership, Detroit, Michigan, USA.

NorthStar Anesthesia, Detroit Medical Center, Detroit, Michigan, USA.

出版信息

Bone Joint J. 2021 Jun;103-B(6):1078-1087. doi: 10.1302/0301-620X.103B6.BJJ-2020-1271.R1.

Abstract

AIMS

It has been suggested that the direct anterior approach (DAA) should be used for total hip arthroplasty (THA) instead of the posterior approach (PA) for better early functional outcomes. We conducted a value-based analysis of the functional outcome and associated perioperative costs, to determine which surgical approach gives the better short-term outcomes and lower costs.

METHODS

This meta-analysis was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) protocol and the Cochrane Handbook. Several online databases were searched. Non-stratified and stratified meta-analyses were conducted to test the confounding biases in the studies which were included. The mean cost and probability were used to determine the added costs of perioperative services.

RESULTS

The DAA group had significantly longer operating times (p < 0.001), reduced length of hospital stay by a mean of 13.4 hours (95% confidence interval (CI) 9.12 to 18; p < 0.001), and greater blood loss (p = 0.030). The DAA group had significantly better functional outcome at three (p < 0.001) and six weeks (p = 0.006) postoperatively according to the Harris Hip Score (HHS). However, there was no significant difference between the groups for the HHS at six to eight weeks (p = 0.230), 12 weeks (p = 0.470), six months (p = 0.740), and one year (p = 0.610), the 12-Item Short Form Survey (SF-12) physical score at six weeks (p = 0.580) and one year (p = 0.360), SF-12 mental score at six weeks (p = 0.170) and one year (p = 0.960), and University of California and Los Angeles (UCLA) activity scale at 12 weeks (p = 0.250). The mean non-stratified and stratified difference in costs for the operating theatre time and blood transfusion were $587.57 (95% CI 263.83 to 1,010.29) to $887.04 (95% CI 574.20 to 1,298.88) and $248.38 (95% CI 1,003.40 to 1,539.90) to $1,162.41 (95% CI 645.78 to 7,441.30), respectively, more for the DAA group. However, the mean differences in costs for the time in hospital were $218.23 and $192.05, respectively, less for the DAA group.

CONCLUSION

The use of the DAA, rather than the PA, in THA has earlier benefits for function and pain. However, these are short-lasting, with no significant differences seen at later intervals. In addition the limited benefits were obtained with higher cumulative costs for DAA. Cite this article:  2021;103-B(6):1078-1087.

摘要

目的

有人提出,为了获得更好的早期功能结果,全髋关节置换术(THA)应采用直接前入路(DAA)而不是后入路(PA)。我们进行了一项基于价值的功能结果和相关围手术期成本分析,以确定哪种手术入路能带来更好的短期结果和更低的成本。

方法

本荟萃分析按照系统评价和荟萃分析的首选报告项目(PRISMA)协议和 Cochrane 手册进行。检索了几个在线数据库。对纳入的研究进行了非分层和分层荟萃分析,以检验混杂偏倚。使用平均成本和概率来确定围手术期服务的附加成本。

结果

DAA 组的手术时间明显更长(p < 0.001),平均住院时间缩短了 13.4 小时(95%置信区间 9.12 至 18;p < 0.001),失血量也明显增加(p = 0.030)。根据 Harris 髋关节评分(HHS),DAA 组在术后 3 周(p < 0.001)和 6 周(p = 0.006)时的功能结果明显更好。然而,两组在术后 6 至 8 周(p = 0.230)、12 周(p = 0.470)、6 个月(p = 0.740)和 1 年(p = 0.610)、SF-12 身体评分在术后 6 周(p = 0.580)和 1 年(p = 0.360)、SF-12 精神评分在术后 6 周(p = 0.170)和 1 年(p = 0.960)以及加州大学洛杉矶分校(UCLA)活动量表在术后 12 周(p = 0.250)时,HHS 评分没有显著差异。手术时间和输血的非分层和分层平均成本差异分别为 587.57 美元(95%置信区间 263.83 至 1,010.29)至 887.04 美元(95%置信区间 574.20 至 1,298.88)和 248.38 美元(95%置信区间 1,003.40 至 1,539.90)至 1,162.41 美元(95%置信区间 645.78 至 7,441.30),DAA 组更高。然而,DAA 组的住院时间成本差异平均为 218.23 美元和 192.05 美元,DAA 组的成本更低。

结论

与 PA 相比,THA 中使用 DAA 具有早期功能和疼痛方面的优势。然而,这些优势是短暂的,在后期没有显著差异。此外,DAA 带来的有限益处是以更高的累计成本为代价的。引用本文:2021;103-B(6):1078-1087.

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