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痴呆对老年髋部骨折手术治疗后结局的影响。

Effect of Dementia on Outcomes After Surgically Treated Hip Fracture in Older Adults.

机构信息

Registry of Senior Australians, South Australian Health and Medical Research Institute, Adelaide, Australia.

Registry of Senior Australians, South Australian Health and Medical Research Institute, Adelaide, Australia; UniSA Allied Health and Human Performance, University of South Australia, Adelaide, Australia.

出版信息

J Arthroplasty. 2021 Sep;36(9):3181-3186.e4. doi: 10.1016/j.arth.2021.04.030. Epub 2021 Apr 30.

Abstract

BACKGROUND

Hip fractures are associated with increased mortality and functional limitations. However, the effect that dementia has on these outcomes in individuals in aged care settings after fracture is not well established. This study examined the association of dementia with post-hip fracture mortality, permanent residential aged care entry, transition care use, and change in activities of daily living (ADL) needs.

METHODS

A retrospective cohort study using data from the Registry of Senior Australians (2003-2015) was conducted. Individuals with a hip fracture while receiving aged care services were included. Associations of dementia with mortality, risks of transition and permanent care use, and ADL needs progression were estimated using multivariable Cox, Fine-Gray, and logistic regression methods, respectively.

RESULTS

Of 4771 individuals evaluated, 76% were women, the median age was 86 years (IQR 82-90), and 71% already lived in permanent residential aged care at the time of fracture. Within two years of their hip fracture, 50.4% (95% CI 48.9%-51.8%) of individuals died, 16.2% (95% CI 14.2%-18.2%) entered a transition care program, 59.1% (95% CI 56.5%-61.7%) entered permanent residential aged care, and 32% had greater ADL needs. Dementia was associated with higher risk of two-year mortality (HR = 1.19, 95% CI 1.09-1.30), 90-day entry into permanent care (sHR = 1.96, 95% CI 1.60-2.38), and increased likelihood of ADL limitations (OR = 1.36, 95% CI 1.00-1.85). Minor differences were seen in transition care use by dementia status.

CONCLUSION

Dementia is a strong risk factor for mortality after hip fractures in individuals in aged care settings and associated with a high risk of entry into permanent care.

LEVEL OF EVIDENCE

Prognostic level III.

摘要

背景

髋部骨折与死亡率增加和功能受限有关。然而,痴呆症对骨折后老年护理环境中个体的这些结果的影响尚未得到充分证实。本研究探讨了痴呆症与髋部骨折后死亡率、永久性居住老年护理入院、过渡性护理使用以及日常生活活动(ADL)需求变化的关系。

方法

使用澳大利亚老年人登记处(2003-2015 年)的数据进行了回顾性队列研究。纳入了在接受老年护理服务时发生髋部骨折的患者。使用多变量 Cox、Fine-Gray 和逻辑回归方法分别估计痴呆症与死亡率、过渡和永久性护理使用风险以及 ADL 需求进展的相关性。

结果

在评估的 4771 名患者中,76%为女性,中位年龄为 86 岁(IQR 82-90),71%在骨折时已经居住在永久性居住老年护理中。在髋部骨折后的两年内,50.4%(95%CI 48.9%-51.8%)的患者死亡,16.2%(95%CI 14.2%-18.2%)进入过渡性护理计划,59.1%(95%CI 56.5%-61.7%)进入永久性居住老年护理,32%的患者 ADL 需求增加。痴呆症与两年死亡率(HR=1.19,95%CI 1.09-1.30)、90 天内进入永久性护理(sHR=1.96,95%CI 1.60-2.38)以及 ADL 受限的可能性增加相关(OR=1.36,95%CI 1.00-1.85)。痴呆症状态对过渡性护理使用的影响差异较小。

结论

痴呆症是老年护理环境中髋部骨折后死亡的一个强有力的危险因素,并与永久性护理入院的高风险相关。

证据水平

预后 III 级。

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