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孕期营养素摄入对婴儿出生体重的影响:系统评价。

The Influence of Nutrients Intake during Pregnancy on Baby's Birth Weight: A Systematic Review.

机构信息

Department of Nutrition, School of Nursing, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.

出版信息

J Trop Pediatr. 2021 May 17;67(2). doi: 10.1093/tropej/fmab034.

DOI:10.1093/tropej/fmab034
PMID:34059907
Abstract

BACKGROUND AND OBJECTIVE

Maternal food intake during pregnancy can substantially interfere in the baby's anthropometric measurements at birth. Our objective was to perform a systematic review that investigate the influence of nutrient intake via food during pregnancy on the baby's anthropometric measurements at birth.

METHODS

A search was performed without time limits on CINAHL, Embase, PubMed, Scopus and Web of Science databases and manual on studies references. All nutrients and baby's anthropometric measurements at birth were included as descriptors.

RESULTS

Thirty articles were included, the majority of prospective cohort studies, with 15.39 (2.36) quality points (maximum value: 22). Thirty-six results of associations were found, of which 17 studies had direct associations between nutrient intake and birth outcomes. Inverse associations were identified in 8 studies and 11 articles showed no significant associations in all analyses. Maternal food intake of vitamin C, calcium and magnesium during pregnancy seems to have a positive influence on the baby's birth weight, while carbohydrates intake have an inverse association with the same outcome.

CONCLUSION

It is suggested that vitamin C, calcium, magnesium and carbohydrates influence on baby's birth weight. So, these specific nutrients need more attention to the consumption, in addition to carried out new studies, with robust methodologies for measuring maternal food consumption and considering the several factors that can interfere in this assessment.

REGISTRATION

This review has been registered to the PROSPERO (International prospective register of systematic reviews) (ID: CRD42020167889).

摘要

背景与目的

孕妇在怀孕期间的食物摄入会对婴儿出生时的人体测量值产生重大影响。我们的目的是进行一项系统评价,调查怀孕期间通过食物摄入营养素对婴儿出生时人体测量值的影响。

方法

无时间限制地在 CINAHL、Embase、PubMed、Scopus 和 Web of Science 数据库以及研究参考文献的手册上进行了搜索。所有营养素和婴儿出生时的人体测量值均被用作描述符。

结果

共纳入 30 篇文章,其中大多数为前瞻性队列研究,质量评分为 15.39(2.36)(最高分:22)。共发现 36 项关联结果,其中 17 项研究表明营养素摄入与出生结局之间存在直接关联。有 8 项研究发现了负向关联,有 11 篇文章在所有分析中均未显示出显著关联。孕妇在怀孕期间摄入维生素 C、钙和镁似乎对婴儿的出生体重有积极影响,而碳水化合物的摄入与同一结果呈负相关。

结论

建议维生素 C、钙、镁和碳水化合物会影响婴儿的出生体重。因此,这些特定的营养素需要更多地关注其摄入量,此外还需要开展新的研究,采用强有力的方法来测量孕妇的食物摄入,并考虑到可能会影响这一评估的多种因素。

注册

本综述已在 PROSPERO(国际前瞻性系统评价注册库)(ID:CRD42020167889)上进行了注册。

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