Burdová Marie Česká, Donátová Kateřina, Mahelková Gabriela, Chrenková Vanda, Dotřelová Dagmar
Department of Ophthalmology, Charles University, 2nd Faculty of Medicine and University Hospital in Motol, Prague, Czech Republic.
Department of Physiology, Charles University, 2nd Faculty of Medicine, Prague, Czech Republic.
J Ophthalmic Inflamm Infect. 2021 Jun 1;11(1):16. doi: 10.1186/s12348-021-00245-3.
A case report of post-traumatic exogenous endophthalmitis caused by Nocardia farcinica, including treatment procedures, microbiology examination, and systemic medications. A 23-year-old male suffered a penetrating corneal injury that was treated with sutures. On the thirteenth day after the final suture was removed, an anterior uveitis developed and progressed to whitish, plump, nodular, and tufted exudates within the anterior chamber over the next 10 days; this led to an indication for intraocular surgery. Anterior chamber lavage and resection of solid fibrinous exudates (using a vitrectomy knife) for a complete microbiological examination were performed. Nocardia farcinica was identified. Systemic medications were chosen according to sensitivity, and a fixed combination of sulfamethoxazole 400 mg/trimethoprim 80 mg was administered long-term (months). In this case, accurate, early detection of an atypical infectious agent and determination of its sensitivity to antibiotic treatment enabled effective treatment that achieved the best functional and anatomical results under the circumstances.
嗜皮诺卡菌引起的创伤后外源性眼内炎病例报告，包括治疗过程、微生物学检查及全身用药情况。一名23岁男性遭受穿透性角膜损伤，接受了缝合治疗。在最后一针缝线拆除后的第13天，发生了前葡萄膜炎，并在接下来的10天内进展为前房内出现白色、饱满、结节状和簇状渗出物；这导致了进行眼内手术的指征。进行了前房灌洗和切除固体纤维蛋白渗出物（使用玻璃体切割刀）以进行完整的微生物学检查。鉴定出嗜皮诺卡菌。根据药敏结果选择全身用药，长期（数月）给予磺胺甲恶唑400mg/甲氧苄啶80mg的固定复方制剂。在该病例中，准确、早期检测出非典型感染病原体并确定其对抗生素治疗的敏感性，使得在当时情况下能够进行有效的治疗，从而取得了最佳的功能和解剖学结果。
