Zayet S, Lang S, Ben Abdallah Y, Klopfenstein T, Gendrin V
Infectious Diseases Department, France.
Pneumology Department, Nord Franche-Comté Hospital, Trévenans, France.
New Microbes New Infect. 2020 Nov 7;38:100808. doi: 10.1016/j.nmni.2020.100808. eCollection 2020 Nov.
We report the case of a 68-year-old man with long-term receipt of steroid therapy who was diagnosed with cerebral abscesses and pulmonary nocardiosis. This patient displayed only respiratory symptoms. Confirmation of species was achieved by specific PCR sequencing of the 16S ribosome RNA in bronchoalveolar lavage cultures. Cerebral magnetic resonance imaging revealed abscesses. Antibiotic therapy with trimethoprim/sulfamethoxazole was prescribed given the results of susceptibility tests and was maintained for 12 months, with no evidence of relapse afterwards.
我们报告了一例长期接受类固醇治疗的68岁男性患者,该患者被诊断为脑脓肿和肺诺卡菌病。该患者仅表现出呼吸道症状。通过对支气管肺泡灌洗培养物中的16S核糖体RNA进行特异性PCR测序来确定菌种。脑部磁共振成像显示有脓肿。根据药敏试验结果,给予甲氧苄啶/磺胺甲恶唑进行抗生素治疗,并持续12个月,此后无复发迹象。