Koca-Ünsal Revan Birke, Ünsal Gürkan, Kasnak Gökhan, Fıratlı Yiğit, Özcan İlknur, Orhan Kaan, Fıratlı Erhan
Department of Periodontology, University of Kyrenia, Faculty of Dentistry, Kyrenia, Cyprus.
Department of Dentomaxillofacial Radiology, Faculty of Dentistry, Near East University, Nicosia, Cyprus.
J Periodontol. 2022 Feb;93(2):187-194. doi: 10.1002/JPER.21-0076. Epub 2021 Jun 14.
Complications after free gingival graft (FGG) operations are generally related to the donor site. The titanium-prepared, platelet-rich fibrin (T-PRF) placement in the donor site accelerate the wound healing and prevent postoperative complications such as pain and hemorrhage. We aim to evaluate the effect of T-PRF regarding vascularization and tissue thickness and to report the advantages of the ultrasonography (US) in FGG.
Ten individuals were divided into two groups as T-PRF and control. While the T-PRF membrane was placed at the donor site in the T-PRF group, a gelatin sponge was placed in the control group. All patients underwent US examination in terms of vascularization and tissue thickness of left and right donor sites. The correlation between the right and left donor sites was analyzed with the Pearson correlation test. Tissue thicknesses and pulsatility index (PI) were analyzed with independent samples t-test. The results were evaluated statistically at the P <0.05 significance level.
The T-PRF group showed increased vascularity which can be interpreted to improve healing in soft tissue. However, not a difference, but a positively very high correlation was observed between the right and left tissue thicknesses (P = 0,00; r = +0902).
Evaluation of tissue thickness and vascularization density of donor sites with US not only increases clinical success rate but also reduces the risk of complications during surgery and postoperative pain in FGG. Studies evaluating T-PRF membrane as palatal dressing after FGG are only clinical, however, the efficiency of T-PRF was evaluated radiologically in this study for the first time.
游离龈瓣移植（FGG）手术后的并发症通常与供区有关。在供区放置钛制备的富血小板纤维蛋白（T-PRF）可加速伤口愈合并预防术后并发症，如疼痛和出血。我们旨在评估T-PRF对血管化和组织厚度的影响，并报告超声检查（US）在FGG中的优势。
将10名个体分为T-PRF组和对照组。T-PRF组在供区放置T-PRF膜，对照组放置明胶海绵。所有患者均接受了关于左右供区血管化和组织厚度的超声检查。用Pearson相关检验分析左右供区之间的相关性。用独立样本t检验分析组织厚度和搏动指数（PI）。结果在P<0.05显著性水平进行统计学评估。
T-PRF组显示血管增多，这可以解释为软组织愈合得到改善。然而，左右组织厚度之间未观察到差异，而是观察到非常高的正相关性（P = 0.00；r = +0.902）。
用超声评估供区的组织厚度和血管化密度不仅可提高FGG的临床成功率，还可降低手术期间的并发症风险和术后疼痛。评估FGG后T-PRF膜作为腭部敷料的研究仅为临床研究，然而，本研究首次通过影像学评估了T-PRF的有效性。
