富血小板纤维蛋白与游离龈瓣移植术在种植术前软组织缺损治疗中的效果

Effect of Platelet-rich Fibrin and Free Gingival Graft in the Treatment of Soft Tissue Defect preceding Implant Placement.

作者信息

Ibraheem Wael

机构信息

Division of Periodontics, Department of Preventive Dental Sciences, College of Dentistry, Jazan University, Jazan Kingdom of Saudi Arabia, Phone: +00966559871000, e-mail:

出版信息

J Contemp Dent Pract. 2018 Jul 1;19(7):895-899.

PMID:30066697

Abstract

INTRODUCTION

Free gingival graft is a procedure that is used to increase keratinized tissue around teeth and edentulous sites for future dental implants. Keratinized tissue is critical for maintainability of surgical site and flap management. Platelet-rich fibrin consists of bioactive and biological components, mainly composed of growth factors. Growth factors attract stem cells to the site of release and stimulate cell proliferation. Moreover, growth factors promote angiogenesis, which accelerates wound healing. Site preparation is critical in implant dentistry, including soft tissue and hard tissue augmentation.

AIM

To improve free gingival graft (FGG) healing by using platelet-rich fibrin (PRF) at the soft tissue defect area of extracted upper right first molar in order to restore keratinized tissue and prepare the site for bone grafting followed by dental implant placement.

CASE REPORT

A healthy female patient, 59 years old, presented to the dental clinic at the University at Buffalo, School of Dental Medicine, seeking dental implants to restore missing teeth. The patient had an extraction for upper right first molar 4 months ago. The surgical extraction left severe soft and hard tissue defects at the site. Free gingival graft was placed at the site to increase keratinized tissue band followed by PRF to improve healing. Cyanoacrylate adhesive was used to stabilize PRF Two months later, a full-thickness flap was reflected, and tenting screws placed with bone grafting at the site. Titanium-reenforced membrane was placed over the bone graft. Three months later, tenting screws were removed and two dental implants were placed at the site.

CONCLUSION

The use of PRF accelerates the healing of FGG. More tissue handling could be achieved by increasing the kera-tinized tissue during surgical procedures.

CLINICAL SIGNIFICANCE

The combination of PRF and FGG could help in the healing process during soft tissue procedures.

摘要

引言

游离龈瓣移植术是一种用于增加牙齿周围和无牙区角化组织以利于未来牙种植的手术。角化组织对于手术部位的可维护性和瓣的处理至关重要。富血小板纤维蛋白由生物活性和生物成分组成，主要由生长因子构成。生长因子吸引干细胞至释放部位并刺激细胞增殖。此外，生长因子促进血管生成，从而加速伤口愈合。种植牙科中的位点预备至关重要，包括软组织和硬组织增量。

目的

通过在拔除的右上第一磨牙软组织缺损区使用富血小板纤维蛋白（PRF）来改善游离龈瓣移植（FGG）的愈合，以恢复角化组织并为骨移植及随后的牙种植体植入准备位点。

病例报告

一名59岁健康女性患者前往布法罗大学牙医学院牙科诊所寻求牙种植以修复缺失牙。该患者4个月前拔除了右上第一磨牙。手术拔除在该部位留下了严重的软硬组织缺损。在该部位放置游离龈瓣移植以增加角化组织带，随后使用PRF以改善愈合。使用氰基丙烯酸酯粘合剂固定PRF。两个月后，掀起全厚瓣，在位点放置定位螺钉并进行骨移植。在骨移植上方放置钛增强膜。三个月后，取出定位螺钉并在位点植入两颗牙种植体。