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磷霉素氨丁三醇治疗慢性前列腺炎疗程延长:一个未知的良好选择。

Prolonged course of Fosfomycin-Trometamol for chronic prostatitis: an unknown good option.

机构信息

Infectious Diseases Department, ELSAN Polyclinique de Limoges, Limoges, France.

出版信息

Scand J Urol. 2021 Aug;55(4):344-345. doi: 10.1080/21681805.2021.1933170. Epub 2021 Jun 1.

Abstract

BACKGROUND

Bacterial prostatitis can be difficult to treat as more and more bacteria are resistant to fluoroquinolone and/or Sulfamethoxazole-Trimethoprim which are the antibiotics of choice. Fosfomycin-Trometamol which is registered for uncomplicated urinary tract infections can be an option when other treatments can't be used.

OBJECTIVE

To describe a case of prostatitis cured using a prolonged course of Fosfomycin-Trometamol. Patient: A 67 years-old man with a chronic bacterial prostatitis, with recurrences for more than 3 years, due to was treated with Fosfomycin-Trometamol 3g once a day for a week followed by 3 months of the same dose every two days. Prostatitis was clinically and bacteriologically cured and no relapse occurred after 6 months of follow-up.

CONCLUSION

Fosfomycin-Trometamol can be a good option for the treatment of bacterial prostatitis when other antibiotics can't be used either for resistance or allergy.

摘要

背景

由于越来越多的细菌对氟喹诺酮类和/或磺胺甲恶唑-甲氧苄啶(这两种抗生素是首选药物)产生耐药性,细菌性前列腺炎的治疗变得愈发困难。当其他治疗方法无法使用时,磷霉素氨丁三醇(一种用于治疗单纯性尿路感染的药物)可以作为一种选择。

病例描述

一名 67 岁男性患有慢性细菌性前列腺炎,反复发作超过 3 年,因对氟喹诺酮类和/或磺胺甲恶唑-甲氧苄啶过敏而采用磷霉素氨丁三醇 3g 每天一次治疗 1 周,然后每两天给予相同剂量的药物 3 个月。经过治疗,患者的前列腺炎在临床和细菌学上均得到治愈,在 6 个月的随访中未再复发。

结论

当其他抗生素因耐药或过敏而无法使用时,磷霉素氨丁三醇可以作为治疗细菌性前列腺炎的一种有效选择。

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