Kojima Ko, Uchida Seiya, Kinoshita Hidenori, Miura Katsukiyo
Department of Applied Chemistry, Graduate School of Science and Engineering, Saitama University, 255 Shimo-ohkubo, Sakura-ku, Saitama 338-8570, Japan.
Org Lett. 2021 Jun 18;23(12):4598-4602. doi: 10.1021/acs.orglett.1c01314. Epub 2021 Jun 1.
We developed a synthetic route to unsymmetrically polysubstituted germoles bearing different substituents from 1-hydrogermyl-4-silyl-1,3-enynes. The reaction proceeded with 0.5 equiv of diisobutylaluminum hydride. Various 2-silylgermoles including benzogermoles were obtained in good to excellent yields. 2-Germylbenzogermoles could be also successfully synthesized from 1-hydrogermyl-4-germyl-1,3-enynes under the same reaction conditions.
我们开发了一种从1-氢锗基-4-硅基-1,3-烯炔制备带有不同取代基的不对称多取代锗茂的合成路线。该反应在0.5当量的二异丁基氢化铝存在下进行。以良好至优异的产率获得了各种2-硅基锗茂，包括苯并锗茂。在相同的反应条件下，也可以从1-氢锗基-4-锗基-1,3-烯炔成功合成2-锗基苯并锗茂。
