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热带地区急性风湿热及相关链球菌感染与同期急性肾小球肾炎的比较

Tropical acute rheumatic fever and associated streptococcal infections compared with concurrent acute glomerulonephritis.

作者信息

Potter E V, Svartman M, Mohammed I, Cox R, Poon-King T, Earle D P

出版信息

J Pediatr. 1978 Feb;92(2):325-33. doi: 10.1016/s0022-3476(78)80036-5.

DOI:10.1016/s0022-3476(78)80036-5
PMID:340631
Abstract

Ninety-three patients with acute rheumatic fever and 195 patients with acute glomerulonephritis were observed in Trinidad during an outbreak of scabies with a high incidence of secondary streptococcal infections. Clinical and laboratory manifestations of ARF were the same as those seen in temperate zones, except that antistreptolysin O titers were less markedly increased. The patients with ARF were similar to those with AGN in respect to sex, race, location of residence, and living conditions, but were older and had markedly fewer skin infections. Currently prevalent nephritogenic streptococcal strains never were isolated from patients with ARF even when M55 streptococci appeared and led to an epidemic of AGN.

摘要

在特立尼达一次疥疮暴发且继发性链球菌感染发病率很高期间,对93例急性风湿热患者和195例急性肾小球肾炎患者进行了观察。急性风湿热的临床和实验室表现与温带地区所见相同,只是抗链球菌溶血素O滴度升高不太明显。急性风湿热患者在性别、种族、居住地点和生活条件方面与急性肾小球肾炎患者相似,但年龄较大,皮肤感染明显较少。即使出现M55链球菌并导致急性肾小球肾炎流行,也从未从急性风湿热患者中分离出当前流行的致肾炎性链球菌菌株。

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