Reid H F, Bassett D C, Poon-King T, Zabriskie J B, Read S E
J Hyg (Lond). 1985 Feb;94(1):61-8. doi: 10.1017/s0022172400061131.
The group G streptococcus has generally not been considered a prominent pathogen. In a 1982 study of the colonization rate by beta-haemolytic streptococci in apparently healthy children, age 5-11 years, 25 of 69 isolates belonged to group G. This surprisingly high rate of group G colonization (14.3%) led to a retrospective study of school surveys in 1967 which showed that the colonization rate with this organism was 2.3% (range 1.3-3.5%). A review of bacitracin-sensitive streptococcal isolates from hospital admissions of patients with acute glomerulonephritis (AGN), rheumatic fever, and their siblings, between January 1967 and July 1980, was conducted. Of 1063 bacitracin-sensitive isolates, 63 were group G, and 52 of these were isolated from AGN patients and their siblings, i.e. 7 from skin lesions of AGN patients, 40 from the throats of siblings and only 5 from the skins of the siblings. The other 11 group G isolates were from rheumatic-fever patients and their siblings. Thus, the group G colonization rate fluctuates in the population. The isolation of only group G streptococci from skin lesions of patients with AGN suggests a possible association between group G streptococcal pyoderma and acute post-streptococcal glomerulonephritis.
G 组链球菌通常不被认为是一种主要的病原体。在一项1982年针对5至11岁看似健康儿童中β溶血性链球菌定植率的研究中，69株分离菌株中有25株属于G组。这一令人惊讶的高G组定植率（14.3%）促使对1967年学校调查进行回顾性研究，结果显示该菌的定植率为2.3%（范围为1.3% - 3.5%）。对1967年1月至1980年7月期间因急性肾小球肾炎（AGN）、风湿热入院患者及其兄弟姐妹中对杆菌肽敏感的链球菌分离菌株进行了回顾性分析。在1063株对杆菌肽敏感的分离菌株中，63株为G组，其中52株分离自AGN患者及其兄弟姐妹，即7株来自AGN患者的皮肤病变，40株来自兄弟姐妹的咽喉部，仅5株来自兄弟姐妹的皮肤。另外11株G组分离菌株来自风湿热患者及其兄弟姐妹。因此，G组在人群中的定植率存在波动。仅从AGN患者皮肤病变中分离出G组链球菌，提示G组链球菌脓皮病与急性链球菌感染后肾小球肾炎之间可能存在关联。
