对克鲁彭科等人的回复。关于“李等人。2020年，ALDH1L1功能丧失与二甲双胍治疗联合降低KRAS驱动的肺癌肿瘤生长，，1382”的评论。
Reply to Krupenko et al. Comment on "Lee et al. The Combination of Loss of ALDH1L1 Function and Phenformin Treatment Decreases Tumor Growth in KRAS-Driven Lung Cancer 2020, , 1382".
作者信息
Lee Seon-Hyeong, Jeon Yoon, Kang Joon-Hee, Jang Hyonchol, Hong Kyeong-Man, Hong Dongwan, Lee Ho, Kim Soo-Youl
机构信息
Division of Cancer Biology, Research Institute, National Cancer Center, Goyang 10408, Korea.
Department of Medical Informatics, College of Medicine, Catholic University of Korea, Seoul 06591, Korea.
出版信息
Cancers (Basel). 2021 May 7;13(9):2238. doi: 10.3390/cancers13092238.
Abstract
In the Cancers paper, we observed the increase ALDH1L1 protein expression following oncogenesis, as well as a therapeutic effect, by deleting the gene in mice, a model of spontaneous non-small cell lung cancer (NSCLC) [...].
摘要
在《癌症》杂志的论文中，我们观察到致癌作用后ALDH1L1蛋白表达增加，以及通过在自发非小细胞肺癌（NSCLC）小鼠模型中删除该基因所产生的治疗效果[……]
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