全胰切除术及自体胰岛细胞移植有哪些新进展？该领域当前进展综述。
What Is New with Total Pancreatectomy and Autologous Islet Cell Transplantation? Review of Current Progress in the Field.
作者信息
Baldwin Xavier L, Williams Brittney M, Schrope Beth, Desai Chirag S
机构信息
Department of Surgery, University of North Carolina in Chapel Hill, Chapel Hill, NC 27599, USA.
Department of Surgery, NewYork-Presbyterian/Columbia University Irving Medical Center, New York, NY 10032, USA.
出版信息
J Clin Med. 2021 May 14;10(10):2123. doi: 10.3390/jcm10102123.
Abstract
Patients with chronic pancreatitis have benefited from total pancreatectomy and autologous islet cell transplantation (TPAIT) since the 1970s. Over the past few decades, improvements have been made in surgical technique and perioperative management that have led to improved success of islet cell function, insulin independence and patient survival. This article focuses on recent updates and advances for the TPAIT procedure that continue to expand and innovate the impact on patients with debilitating disease.
摘要
自20世纪70年代以来，慢性胰腺炎患者已从全胰切除术和自体胰岛细胞移植（TPAIT）中受益。在过去几十年里，手术技术和围手术期管理都有了改进，这使得胰岛细胞功能、胰岛素自主性和患者生存率都得到了提高。本文重点介绍了TPAIT手术的最新进展，这些进展不断扩大并创新了对患有衰弱性疾病患者的影响。
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本文引用的文献
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Transpl Int. 2021 Mar;34(3):593-595. doi: 10.1111/tri.13821. Epub 2021 Feb 9.
2
Long-term Stability of β-Cell Graft Function After Total Pancreatectomy and Islet Autotransplantation.全胰切除术后胰岛自体移植后β细胞移植功能的长期稳定性
Pancreas. 2021 Jan 1;50(1):e2-e4. doi: 10.1097/MPA.0000000000001711.
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Neither amyloid depositions nor hepatic steatosis are associated with marginal islet mass early after autotransplantation.自体移植术后早期，淀粉样蛋白沉积和肝脂肪变性均与边缘胰岛质量无关。
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