Baldwin Xavier L, Williams Brittney M, Schrope Beth, Desai Chirag S
Department of Surgery, University of North Carolina in Chapel Hill, Chapel Hill, NC 27599, USA.
Department of Surgery, NewYork-Presbyterian/Columbia University Irving Medical Center, New York, NY 10032, USA.
J Clin Med. 2021 May 14;10(10):2123. doi: 10.3390/jcm10102123.
Patients with chronic pancreatitis have benefited from total pancreatectomy and autologous islet cell transplantation (TPAIT) since the 1970s. Over the past few decades, improvements have been made in surgical technique and perioperative management that have led to improved success of islet cell function, insulin independence and patient survival. This article focuses on recent updates and advances for the TPAIT procedure that continue to expand and innovate the impact on patients with debilitating disease.
自20世纪70年代以来，慢性胰腺炎患者已从全胰切除术和自体胰岛细胞移植（TPAIT）中受益。在过去几十年里，手术技术和围手术期管理都有了改进，这使得胰岛细胞功能、胰岛素自主性和患者生存率都得到了提高。本文重点介绍了TPAIT手术的最新进展，这些进展不断扩大并创新了对患有衰弱性疾病患者的影响。
