Department of Experimental Medicine, University of Genoa, 16132 Genoa, Italy.
Texas Biomedical Research Institute, 8715 W. Military Drive, San Antonio, TX 78227, USA.
Int J Environ Res Public Health. 2021 May 18;18(10):5395. doi: 10.3390/ijerph18105395.
Military personnel are frequently exposed to environmental pollutants that can cause a variety of diseases.
This review analyzed publications regarding epidemiological and biomonitoring studies on occupationally-exposed military personnel.
The exposures include sulfur mustard, organ chlorines, combustion products, fuel vapors, and ionizing and exciting radiations. Important factors to be considered are the lengths and intensities of exposures, its proximity to the sources of environmental pollutants, as well as confounding factors (cigarette smoke, diet, photo-type, healthy warrior effect, etc.). Assessment of environmental and individual exposures to pollutants is crucial, although often omitted, because soldiers have often been evaluated based on reported health problems rather than on excessive exposure to pollutants. Biomarkers of exposures and effects are tools to explore relationships between exposures and diseases in military personnel. Another observation from this review is a major problem from the lack of suitable control groups.
This review indicates that only studies which analyzed epidemiological and molecular biomarkers in both exposed and control groups would provide evidence-based conclusions on exposure and disease risk in military personnel.
军人经常接触环境污染物,这些污染物可能导致多种疾病。
本综述分析了关于职业暴露于军事人员的流行病学和生物监测研究的出版物。
暴露包括硫芥子气、有机氯、燃烧产物、燃料蒸气以及电离和激发辐射。需要考虑的重要因素包括暴露的长度和强度、其与环境污染物源的接近程度以及混杂因素(如香烟烟雾、饮食、光型、健康战士效应等)。尽管经常被忽略,但评估环境和个体对污染物的暴露情况至关重要,因为士兵通常是根据报告的健康问题而不是对污染物的过度暴露来进行评估的。暴露和效应的生物标志物是探索军事人员暴露与疾病之间关系的工具。本综述的另一个观察结果是缺乏合适对照组所导致的一个主要问题。
本综述表明,只有同时分析暴露组和对照组的流行病学和分子生物标志物的研究,才能为军事人员暴露和疾病风险提供基于证据的结论。