Merad Yassine, Derrar Hichem, Belmokhtar Zoubir, Belkacemi Malika
Department Parasitology-Mycology, 'Hassani Abdelkader' Hospital, UDL Faculty of Medicine, Laboratoire de Synthèse de L'information Environementale, UDL, Sidi-Bel-Abbes 22000, Algeria.
Department of Pulmonary Diseases, 'Hassani Abdelkader' Hospital, UDL Faculty of Medicine, Sidi-Bel-Abbes 22000, Algeria.
Pathogens. 2021 May 23;10(6):643. doi: 10.3390/pathogens10060643.
Superficial and cutaneous aspergillosis is a rare fungal disease that is restricted to the outer layers of the skin, nails, and the outer auditory canal, infrequently invading the deeper tissue and viscera, particularly in immunocompromised patients. These mycoses are acquired through two main routes: direct traumatic inoculation or inhalation of airborne fungal spores into paranasal sinuses and lungs. Lesions are classified into three categories: otomycosis, onychomycosis, and cutaneous aspergillosis. Superficial and cutaneous aspergillosis occurs less frequently and therefore remains poorly characterized; it usually involves sites of superficial trauma-namely, at or near intravenous entry catheter site, at the point of traumatic inoculation (orthopaedic inoculation, ear-self-cleaning, schizophrenic ear self-injuries), at surgery incision, and at the site of contact with occlusive dressings, especially in burn patients. Onychomycosis and otomycosis are more seen in immunocompetent patients, while cutaneous aspergillosis is widely described among the immunocompromised individuals. This paper is a review of related literature.
浅表及皮肤曲霉病是一种罕见的真菌病,局限于皮肤外层、指甲和外耳道,很少侵犯深部组织和内脏,尤其是在免疫功能低下的患者中。这些真菌病主要通过两种途径获得:直接创伤接种或吸入空气中的真菌孢子进入鼻窦和肺部。病变分为三类:耳真菌病、甲真菌病和皮肤曲霉病。浅表及皮肤曲霉病发病率较低,因此特征仍不明确;它通常累及浅表创伤部位,即静脉穿刺导管部位或其附近、创伤接种点(骨科接种、耳部自行清洁、精神分裂症患者耳部自我伤害)、手术切口以及与闭塞性敷料接触的部位,尤其是烧伤患者。甲真菌病和耳真菌病在免疫功能正常的患者中更为常见,而皮肤曲霉病在免疫功能低下的个体中广泛存在。本文是对相关文献的综述。