一组有严重症状的老年主动脉瓣狭窄患者的衰弱评估：来自严重主动脉瓣狭窄衰弱评估（FRESAS）注册研究的见解
Frailty Assessment in a Cohort of Elderly Patients with Severe Symptomatic Aortic Stenosis: Insights from the FRailty Evaluation in Severe Aortic Stenosis (FRESAS) Registry.
作者信息
Solla-Suárez Pablo, Avanzas Pablo, Pascual Isaac, Bermúdez-Menéndez De La Granda Manuel, Almendarez Marcel, Arche-Coto Jose M, Hernández-Vaquero Daniel, Lorca Rebeca, López-Álvarez Eva, Álvarez-Velasco Rut, Moreno-Planillo Carmen, Morís de la Tassa César, Gutiérrez-Rodríguez José
机构信息
Área de Gestión Clínica de Geriatría, Hospital Monte Naranco, 33011 Oviedo, Spain.
Instituto de Investigación Sanitaria del Principado de Asturias, 33011 Oviedo, Spain.
出版信息
J Clin Med. 2021 May 27;10(11):2345. doi: 10.3390/jcm10112345.
BACKGROUND
Precise evaluation of the degree of frailty is a fundamental part of the global geriatric assessment that helps to avoid therapies that could be futile. Our main objective was to determine the prevalence of frailty in a specific consult of patients undergoing aortic valve replacement.
METHODS
From May 2018 to February 2020, all consecutive patients ≥75 years old, with severe symptomatic aortic stenosis, undergoing valve replacement in the Principality of Asturias (Northern Spain) were evaluated.
RESULTS
A total of 286 patients were assessed. The mean age was 84 ± 4.01 years old; 175 (61.2%) were female. The short performance physical battery score was 8.5 ± 2.4 and the prevalence of frailty was 19.6% (56 patients). In the multivariable analysis, age, Barthel index and atrial fibrillation were independent predictors of frailty.
CONCLUSIONS
The prevalence of frailty in our sample patients undergoing aortic valve replacement, evaluated by a standardized protocol, was 19.6%.
背景
准确评估衰弱程度是全球老年医学评估的基本组成部分，有助于避免无效治疗。我们的主要目标是确定接受主动脉瓣置换术的特定患者群体中衰弱的患病率。
方法
2018年5月至2020年2月，对西班牙北部阿斯图里亚斯公国所有连续的、年龄≥75岁、患有严重症状性主动脉瓣狭窄且正在接受瓣膜置换术的患者进行评估。
结果
共评估了286例患者。平均年龄为84±4.01岁；175例（61.2%）为女性。简易体能状况量表评分为8.5±2.4，衰弱患病率为19.6%（56例患者）。在多变量分析中，年龄、巴氏指数和心房颤动是衰弱的独立预测因素。
结论
通过标准化方案评估，我们样本中接受主动脉瓣置换术的患者衰弱患病率为19.6%。
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