Pichler M, Linzmayer L, Grünberger J, Wessely P
Bereich für klinische Psychodiagnostik, Psychiatrische Universitätsklinik, Wien.
Wien Klin Wochenschr. 1988 Jun 10;100(12):385-91.
The aim of this study was to investigate the physiological and psychological mechanisms underlying migraine, 21 patients with migraine, 21 healthy controls and a group of 21 asthmatics participated in the investigation. All patients and controls were female. Using flicker frequency analysis we determined unspecific cortical activation, whereas autonomic activation was measured by means of the skin conductance level and the skin conductance response. Furthermore, stress management was objectivated by a self-rating scale (SVF). Our findings suggest the hypothesis of inadequate regulation of autonomic especially sympathetic reactions, which along with inadequate stress overcoming mechanisms appear to be of importance in the triggering of migraine attacks.
本研究旨在探究偏头痛背后的生理和心理机制，21名偏头痛患者、21名健康对照者以及一组21名哮喘患者参与了此次调查。所有患者和对照者均为女性。我们通过闪烁频率分析来测定非特异性皮质激活，而自主神经激活则通过皮肤电导率水平和皮肤电导率反应进行测量。此外，应激管理通过一份自评量表（SVF）进行客观评估。我们的研究结果提出了自主神经尤其是交感神经反应调节不足的假说，这与应激克服机制不足似乎在偏头痛发作的触发中起着重要作用。
