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["健康"老年人中的"异常"神经学表现]

["Abnormal" neurologic findings in the "healthy" elderly].

作者信息

Schiffter R

机构信息

Krankenhaus Am Urban, Berlin.

出版信息

Z Gerontol. 1988 May-Jun;21(3):122-5.

PMID:3407279
Abstract

Neuropathological changes and clinical neurological findings of the nervous system of healthy, old people (more than 80 years old) are referenced according to the literature. In addition, the results of a clinical neurological examination of 86 healthy senior citizens (average age: 83.6 years) are demonstrated. The respective findings are summarized in a table according to their frequency. The involution of the human nervous system with age results neuropathologically and clinically-neurologically in damage to the frontal lobe (disinhibition of archaic reflexes), the extrapyramidal system (Parkinsonian walking pattern), the posterior tract of the spine (unsteadiness of walking), and the peripheral nervous system (e.g. loss of the achilles tendon reflex). The Parkinsonian-like walking pattern of the healthy old-aged human is thought to be a disinhibition of an archaic pattern of posture and movement. Brief suggestions for differential diagnosis and therapy are presented.

摘要

根据文献参考了健康老年人(80岁以上)神经系统的神经病理学变化和临床神经学表现。此外,还展示了86名健康老年人(平均年龄:83.6岁)的临床神经学检查结果。各自的发现根据其出现频率汇总在一张表格中。随着年龄增长,人类神经系统的退化在神经病理学和临床神经学上导致额叶损伤(原始反射抑制解除)、锥体外系损伤(帕金森步态模式)、脊髓后束损伤(行走不稳)以及周围神经系统损伤(如跟腱反射消失)。健康老年人的帕金森样步态模式被认为是一种原始姿势和运动模式的抑制解除。文中还给出了鉴别诊断和治疗的简要建议。

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J Neurol. 2006 May;253(5):578-89. doi: 10.1007/s00415-005-0064-0. Epub 2005 Nov 23.