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评估COVID-19对结核病和艾滋病服务实时影响的运筹学研究:津巴布韦哈拉雷卫生设施的经验与应对措施

Operational Research to Assess the Real-Time Impact of COVID-19 on TB and HIV Services: The Experience and Response from Health Facilities in Harare, Zimbabwe.

作者信息

Thekkur Pruthu, Takarinda Kudakwashe C, Timire Collins, Sandy Charles, Apollo Tsitsi, Kumar Ajay M V, Satyanarayana Srinath, Shewade Hemant D, Khogali Mohammed, Zachariah Rony, Rusen I D, Berger Selma Dar, Harries Anthony D

机构信息

International Union Against Tuberculosis and Lung Disease (The Union), 75006 Paris, France.

The Union South-East Asia Office, New Delhi 110016, India.

出版信息

Trop Med Infect Dis. 2021 May 31;6(2):94. doi: 10.3390/tropicalmed6020094.

DOI:10.3390/tropicalmed6020094
PMID:34072803
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8261627/
Abstract

When COVID-19 was declared a pandemic, there was concern that TB and HIV services in Zimbabwe would be severely affected. We set up real-time monthly surveillance of TB and HIV activities in 10 health facilities in Harare to capture trends in TB case detection, TB treatment outcomes and HIV testing and use these data to facilitate corrective action. Aggregate data were collected monthly during the COVID-19 period (March 2020-February 2021) using EpiCollect5 and compared with monthly data extracted for the pre-COVID-19 period (March 2019-February 2020). Monthly reports were sent to program directors. During the COVID-19 period, there was a decrease in persons with presumptive pulmonary TB (40.6%), in patients registered for TB treatment (33.7%) and in individuals tested for HIV (62.8%). The HIV testing decline improved in the second 6 months of the COVID-19 period. However, TB case finding deteriorated further, associated with expiry of diagnostic reagents. During the COVID-19 period, TB treatment success decreased from 80.9 to 69.3%, and referral of HIV-positive persons to antiretroviral therapy decreased from 95.7 to 91.7%. Declining trends in TB and HIV case detection and TB treatment outcomes were not fully redressed despite real-time monthly surveillance. More support is needed to transform this useful information into action.

摘要

当新冠病毒病被宣布为大流行病时,人们担心津巴布韦的结核病和艾滋病服务会受到严重影响。我们在哈拉雷的10家医疗机构建立了结核病和艾滋病活动的每月实时监测,以掌握结核病病例发现、结核病治疗结果以及艾滋病检测的趋势,并利用这些数据促进采取纠正措施。在新冠病毒病期间(2020年3月至2021年2月),每月使用EpiCollect5收集汇总数据,并与新冠病毒病之前时期(2019年3月至2020年2月)提取的月度数据进行比较。每月报告发送给项目负责人。在新冠病毒病期间,疑似肺结核患者人数减少了40.6%,登记接受结核病治疗的患者减少了33.7%,接受艾滋病检测的个人减少了62.8%。在新冠病毒病期间的后6个月,艾滋病检测下降的情况有所改善。然而,结核病病例发现情况进一步恶化,这与诊断试剂过期有关。在新冠病毒病期间,结核病治疗成功率从80.9%降至69.3%,将艾滋病毒阳性者转介接受抗逆转录病毒治疗的比例从95.7%降至91.7%。尽管进行了每月实时监测,但结核病和艾滋病病例发现以及结核病治疗结果的下降趋势并未得到充分纠正。需要更多支持将这些有用信息转化为行动。

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