单核细胞增生李斯特菌脑干脑炎中的翁丁氏诅咒。

Ondine's curse in listeria monocytogenes brain stem encephalitis.

作者信息

Jensen T H, Hansen P B, Brodersen P

机构信息

Department of Infectious Disease, Rigshospitalet, Copenhagen, Denmark.

出版信息

Acta Neurol Scand. 1988 Jun;77(6):505-6. doi: 10.1111/j.1600-0404.1988.tb05949.x.

DOI:10.1111/j.1600-0404.1988.tb05949.x

PMID:3407390

Abstract

A case of necrotizing brain stem encephalitis due to listeria monocytogenes is described in a 48-year-old man who had brain stem encephalitis of complicated course and with selective destruction of the vasomotoric and respiratory centers. He developed that very rare Ondine's curse syndrome, being only able to breathe when awake. The literature on Ondine's curse and brain stem encephalitis due to LM is reviewed. Brain stem encephalitis has a mortality near 100%. The only treatment for Ondine's curse is lifelong artificial ventilation.

摘要

本文描述了一例由单核细胞增生李斯特菌引起的坏死性脑干脑炎病例，患者为一名48岁男性，患有病程复杂的脑干脑炎，血管运动中枢和呼吸中枢受到选择性破坏。他患上了极为罕见的翁丁氏咒诅综合征，仅在清醒时能够呼吸。本文回顾了关于翁丁氏咒诅以及由单核细胞增生李斯特菌引起的脑干脑炎的文献。脑干脑炎的死亡率接近100%。翁丁氏咒诅的唯一治疗方法是终身人工通气。