Department of Pediatrics, Division of Neonatal-Perinatal Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD.
Department of Pediatrics, Division of Neonatal-Perinatal Medicine, Medical University of South Carolina, Shawn Jenkins Children's Hospital, Charleston, SC.
Neoreviews. 2021 Jun;22(6):e360-e369. doi: 10.1542/neo.22-6-e360.
In preterm infants, the goal of aggressive extrauterine nutritional management is to mimic in utero growth and nutrient accretion. Over the latter half of the 20th century, nutritional optimization through the practice of fortifying human milk rose to practice with increased survival rates in preterm infants of younger gestational age. The quest for optimal preterm fortification and nutrition remains a contentious area of debate. This review aims to summarize the historical perspectives of human milk fortification as well as the current literature advocating for the use of liquid human milk fortifiers in enterally fed premature infants.
在早产儿中，积极的宫外营养管理的目标是模拟宫内生长和营养积累。在 20 世纪后半叶，通过强化人乳的实践实现营养优化，使得早产儿的存活率在更小胎龄时提高。对最佳早产儿强化和营养的追求仍然是一个有争议的辩论领域。本综述旨在总结人乳强化的历史观点以及目前提倡在经肠喂养的早产儿中使用液态人乳强化剂的文献。
