Contreras Chova Francisco, Villanueva-García Andrea, González-Boyero J L, Campos-Martínez Ana M, Blanca-Jover Enrique, Jerez-Calero Antonio E, Uberos-Fernández José
Pediatrics and Neonatology, Hospital Universitario San Cecilio, Granada, ESP.
Cureus. 2024 Nov 10;16(11):e73380. doi: 10.7759/cureus.73380. eCollection 2024 Nov.
Breast milk is the best source of nourishment for both full-term and preterm newborns. However, in preterm newborns, exclusive breastfeeding can lead to nutritional deficiencies, with short- and long-term consequences on growth and neurocognitive development. Breast milk fortification is a widely used strategy to provide an adequate nutritional profile to these patients. There is currently a great heterogeneity in terms of fortification patterns and the type of fortifier. The present systematic review summarizes the current scientific evidence to evaluate the different strategies for fortification of human milk in preterm infants, their possible differences on benefits, and the hypothetical impact on prematurity outcomes.
母乳是足月儿和早产儿最佳的营养来源。然而，对于早产儿来说，纯母乳喂养可能会导致营养缺乏，对生长和神经认知发育产生短期和长期影响。母乳强化是一种广泛应用的策略，可为这些患儿提供充足的营养。目前，在强化模式和强化剂类型方面存在很大的异质性。本系统评价总结了当前的科学证据，以评估早产儿母乳强化的不同策略、它们在益处方面可能存在的差异以及对早产结局的潜在影响。
