Chemistry and Chemical Engineering College, Qufu Normal University, Qufu 273165, PR China.
Anal Chem. 2021 Jun 15;93(23):8219-8227. doi: 10.1021/acs.analchem.1c00916. Epub 2021 Jun 2.
Facile and sensitive determination of formaldehyde (FA) in indoor environments still remains challenging. Herein, a fluorescent probe, termed PHN@MOF, was synthesized by embedding the fluorescent molecule of -propyl-4-hydrazine-naphthalimide (PHN) into a metal-organic framework (MOF) for sensitive and visual monitoring of FA. The hydrazine group of PHN acts as the specific reaction group with FA based on the condensation reaction. The host of MOF (UiO-66-NH) offers the surrounding confinement space required for the reaction. Owing to the enrichment effect and molecular sieve selection of UiO-66-NH to FA, PHN@MOF, compared with free PHN, exhibits very high sensitivity and selectivity based on space confinement-induced sensitivity enhancement (SCISE). Moreover, the fluorescence of UiO-66-NH offers a reference signal for FA detection. Using this ratiometric fluorescent PHN@MOF probe, a colorimetric gel plate and test paper were developed and used to visually monitor FA in air.
在室内环境中，简便且灵敏地测定甲醛（FA）仍然具有挑战性。在此，通过将荧光分子 - 丙基-4-肼萘酰亚胺（PHN）嵌入金属-有机骨架（MOF）中，合成了一种荧光探针，称为 PHN@MOF，用于灵敏和可视化监测 FA。PHN 的肼基作为与 FA 发生缩合反应的特定反应基团。MOF（UiO-66-NH）的主体为反应提供了所需的周围限制空间。由于 UiO-66-NH 对 FA 的富集效应和分子筛选择作用，与游离 PHN 相比，基于空间限制诱导的灵敏度增强（SCISE），PHN@MOF 表现出非常高的灵敏度和选择性。此外，UiO-66-NH 的荧光为 FA 检测提供了参考信号。使用这种比率荧光 PHN@MOF 探针，开发了比色凝胶板和试纸，并用于空气 FA 的可视化监测。
