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外科医生在治疗肺癌患者中的作用。一篇更新文章。

The role of the surgeon in treating patients with lung cancer. An updating article.

机构信息

MD, PhD. Full Professor, Thoracic Surgery Program, Instituto do Coração (InCor), Hospital das Clínicas (HC), Faculdade de Medicina da Universidade de São Paulo (FMUSP), São Paulo (SP), Brazil; Cardiothoracic Surgeon, Hospital Beneficência Portuguesa (BP), São Paulo (SP), Brazil.

MD, PhD. Thoracic Surgeon, Hospital Beneficência Portuguesa (BP) and Hospital Sírio-Libanês, São Paulo (SP), Brazil.

出版信息

Sao Paulo Med J. 2021 May 28;139(3):293-300. doi: 10.1590/1516-3180.2020.0763.16022021. eCollection 2021.

Abstract

Lung cancer is a type of neoplasia with one of the highest incidences worldwide and is the largest cause of mortality due to cancer in the world today. It is classified according to its histological and biological characteristics, which will determine its treatment and prognosis. Non-small cell lung cancer accounts for 85% of the cases, and these are the cases that surgeons mostly deal with. Small cell lung cancer accounts for the remaining 15%. Surgery is the main method for treating early stage lung cancer, and lobectomy is the preferred procedure for treating primary lung cancer, while sublobar resection is an alternative for patients with poor reserve or with very small tumors. Surgeons need to be trained to use the resources and techniques available for lung resection, including less invasive approaches such as video-assisted thoracoscopic surgery (VATS) and robotic-assisted thoracoscopic surgery (RATS), and need to be familiar with new oncological approaches, including curative, adjuvant or palliative treatments for patients with lung cancer.

摘要

肺癌是一种肿瘤,其发病率在全球范围内居于前列,也是当今世界癌症死亡的主要原因。肺癌根据其组织学和生物学特征进行分类,这将决定其治疗和预后。非小细胞肺癌占病例的 85%,这些是外科医生主要处理的病例。小细胞肺癌占剩余的 15%。手术是治疗早期肺癌的主要方法,肺叶切除术是治疗原发性肺癌的首选方法,而对于储备功能差或肿瘤非常小的患者,亚肺叶切除术是一种替代方法。外科医生需要接受培训,以利用肺切除术的资源和技术,包括微创方法,如电视辅助胸腔镜手术(VATS)和机器人辅助胸腔镜手术(RATS),并需要熟悉新的肿瘤学方法,包括对肺癌患者进行根治性、辅助性或姑息性治疗。

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Osimertinib in Resected -Mutated Non-Small-Cell Lung Cancer.奥希替尼治疗可切除突变型非小细胞肺癌。
N Engl J Med. 2020 Oct 29;383(18):1711-1723. doi: 10.1056/NEJMoa2027071. Epub 2020 Sep 19.
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Reduced Lung-Cancer Mortality with Volume CT Screening in a Randomized Trial.随机试验中 CT 容积筛查降低肺癌死亡率
N Engl J Med. 2020 Feb 6;382(6):503-513. doi: 10.1056/NEJMoa1911793. Epub 2020 Jan 29.
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Surgical Treatment of Lung Cancer.肺癌的外科治疗
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