Pérez R E, Smith M, McClendon J, Kim J, Eugenio N
Infectious Disease Department, University of California, Irvine.
Am J Med. 1988 Feb;84(2):359-62. doi: 10.1016/0002-9343(88)90441-x.
An adult patient survived a brain abscess with Pseudallescheria boydii. She received intraventricular miconazole, 20 mg every 72 hours (minimal inhibitory concentration = 0.4 microgram/ml), and surgery. The abscess resulted from an infected central venous catheter (Port-A-Cath) and steroid therapy. Miconazole caused a ventriculitis. There are 12 reported cases of P. boydii brain abscesses from 1965 to 1985 with only two survivors.
一名成年患者存活于由博伊德假阿利什菌引起的脑脓肿。她接受了脑室内注射咪康唑治疗,每72小时注射20毫克(最低抑菌浓度=0.4微克/毫升),并接受了手术治疗。该脓肿由感染的中心静脉导管(输液港)和类固醇治疗引起。咪康唑引发了脑室炎。1965年至1985年期间共报告了12例博伊德假阿利什菌脑脓肿病例,仅有两名幸存者。