• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

两性霉素B和抗真菌唑类单独及联合使用对波氏假阿利什菌的活性。

Activities of amphotericin B and antifungal azoles alone and in combination against Pseudallescheria boydii.

作者信息

Walsh T J, Peter J, McGough D A, Fothergill A W, Rinaldi M G, Pizzo P A

机构信息

Infectious Diseases Section, National Cancer Institute, Bethesda, Maryland, USA.

出版信息

Antimicrob Agents Chemother. 1995 Jun;39(6):1361-4. doi: 10.1128/AAC.39.6.1361.

DOI:10.1128/AAC.39.6.1361
PMID:7574531
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC162742/
Abstract

In order to develop new approaches to treatment of infections due to Pseudallescheria boydii, the in vitro antifungal activity of amphotericin B alone and in combination with miconazole, itraconazole, and fluconazole was studied. Combinations of amphotericin B and antifungal azoles were synergistic, additive, or indifferent in their interaction against P. boydii. Antagonism was not observed.

摘要

为了开发治疗波氏假阿利什菌感染的新方法，研究了两性霉素B单独以及与咪康唑、伊曲康唑和氟康唑联合使用时的体外抗真菌活性。两性霉素B与抗真菌唑类药物联合使用时，在抗波氏假阿利什菌的相互作用中表现为协同、相加或无相互作用。未观察到拮抗作用。

相似文献

1
Activities of amphotericin B and antifungal azoles alone and in combination against Pseudallescheria boydii.两性霉素B和抗真菌唑类单独及联合使用对波氏假阿利什菌的活性。
Antimicrob Agents Chemother. 1995 Jun;39(6):1361-4. doi: 10.1128/AAC.39.6.1361.
2
Efficacy of amphotericin B and azoles alone and in combination against disseminated trichosporonosis in neutropenic mice.两性霉素B和唑类药物单独及联合应用对中性粒细胞减少小鼠播散性毛孢子菌病的疗效。
Chemotherapy. 1998 Jan-Feb;44(1):55-62. doi: 10.1159/000007091.
3
Effect of increasing inoculum sizes of pathogenic filamentous fungi on MICs of antifungal agents by broth microdilution method.通过肉汤微量稀释法增加致病丝状真菌接种量对抗真菌剂最低抑菌浓度的影响。
J Clin Microbiol. 1995 May;33(5):1302-7. doi: 10.1128/jcm.33.5.1302-1307.1995.
4
Antifungal susceptibilities of the species of the Pseudallescheria boydii complex.波氏假阿利什菌复合体各菌种的抗真菌药敏性
Antimicrob Agents Chemother. 2006 Dec;50(12):4211-3. doi: 10.1128/AAC.00981-06. Epub 2006 Oct 2.
5
Post-antibiotic effect and post-expositional polyene antagonism of azole antifungal agents in Candida albicans: dependence on substance lipophilia.唑类抗真菌剂对白色念珠菌的抗生素后效应及暴露后多烯拮抗作用：取决于物质亲脂性。
Mycoses. 1995 Nov-Dec;38(11-12):435-42. doi: 10.1111/j.1439-0507.1995.tb00016.x.
6
Susceptibility of clinical isolates of Fusarium to antifungal drugs.镰刀菌临床分离株对抗真菌药物的敏感性
Mycoses. 1996 Jan-Feb;39(1-2):37-40. doi: 10.1111/j.1439-0507.1996.tb00081.x.
7
In vitro antifungal activity of the new triazole D0870 against Penicillium marneffei compared with that of amphotericin B, fluconazole, itraconazole, miconazole and flucytosine.新型三唑类药物D0870对马尔尼菲青霉菌的体外抗真菌活性与两性霉素B、氟康唑、伊曲康唑、咪康唑和氟胞嘧啶的比较。
Mycoses. 1996 Nov-Dec;39(11-12):453-6. doi: 10.1111/j.1439-0507.1996.tb00096.x.
8
In vitro interaction of terbinafine with itraconazole, fluconazole, amphotericin B and 5-flucytosine against Aspergillus spp.特比萘芬与伊曲康唑、氟康唑、两性霉素B及5-氟胞嘧啶在体外对曲霉属真菌的相互作用
J Antimicrob Chemother. 2002 Aug;50(2):189-94. doi: 10.1093/jac/dkf111.
9
In vitro activities of terbinafine in combination with fluconazole and itraconazole against isolates of Candida albicans with reduced susceptibility to azoles.特比萘芬与氟康唑及伊曲康唑联合应用对唑类药物敏感性降低的白色念珠菌分离株的体外活性。
Antimicrob Agents Chemother. 1997 Aug;41(8):1812-4. doi: 10.1128/AAC.41.8.1812.
10
In vitro susceptibility of Trichosporon beigelii to antifungal agents.白吉利丝孢酵母对抗真菌药物的体外敏感性
J Chemother. 1996 Dec;8(6):445-8. doi: 10.1179/joc.1996.8.6.445.

引用本文的文献

1
Cutaneous infection in a patient with metastatic renal cell carcinoma.转移性肾细胞癌患者的皮肤感染
JAAD Case Rep. 2024 Aug 3;52:60-62. doi: 10.1016/j.jdcr.2024.07.013. eCollection 2024 Oct.
2
Update on therapeutic approaches for invasive fungal infections in adults.成人侵袭性真菌感染治疗方法的最新进展。
Ther Adv Infect Dis. 2024 Jan 20;11:20499361231224980. doi: 10.1177/20499361231224980. eCollection 2024 Jan-Dec.
3
YgfB increases β-lactam resistance in Pseudomonas aeruginosa by counteracting AlpA-mediated ampDh3 expression.YgfB 通过拮抗 AlpA 介导的 ampDh3 表达增加铜绿假单胞菌对β-内酰胺类抗生素的耐药性。
Commun Biol. 2023 Mar 10;6(1):254. doi: 10.1038/s42003-023-04609-4.
4
Lactobacillus rhamnosus and Staphylococcus epidermidis in gut microbiota: in vitro antimicrobial resistance.肠道微生物群中的鼠李糖乳杆菌和表皮葡萄球菌：体外抗菌耐药性
AMB Express. 2022 Oct 3;12(1):128. doi: 10.1186/s13568-022-01468-w.
5
Repurposing of auranofin and honokiol as antifungals against species and the related fungus .将金诺芬和厚朴酚重新用于抗 和相关真菌的抗真菌药物。
Virulence. 2021 Dec;12(1):1076-1090. doi: 10.1080/21505594.2021.1909266.
6
In vitro susceptibility testing for black grain eumycetoma causative agents.体外药敏试验对黑色颗粒外瓶霉病致病因子。
Trans R Soc Trop Med Hyg. 2021 Apr 14;115(4):343-354. doi: 10.1093/trstmh/traa184.
7
Management of pulmonary infection by thoracoscopic surgery in an immunocompetent woman.免疫功能正常女性肺部感染的胸腔镜手术治疗
J Int Med Res. 2020 Jul;48(7):300060520931620. doi: 10.1177/0300060520931620.
8
Filamentous fungal endophthalmitis: results of combination therapy with intravitreal amphotericin B and voriconazole.丝状真菌性眼内炎：玻璃体内注射两性霉素B和伏立康唑联合治疗的结果
Clin Ophthalmol. 2015 Apr 13;9:649-55. doi: 10.2147/OPTH.S80387. eCollection 2015.
9
Refractory Scedosporium apiospermum Keratitis Successfully Treated with Combination of Amphotericin B and Voriconazole.两性霉素B与伏立康唑联合成功治疗难治性尖端赛多孢菌角膜炎
Case Rep Ophthalmol Med. 2013;2013:413953. doi: 10.1155/2013/413953. Epub 2013 Feb 20.
10
In vitro interaction of voriconazole and anidulafungin against triazole-resistant Aspergillus fumigatus.体外伏立康唑和阿尼芬净对唑类耐药烟曲霉的相互作用。
Antimicrob Agents Chemother. 2013 Feb;57(2):796-803. doi: 10.1128/AAC.00980-12. Epub 2012 Nov 26.

本文引用的文献

1
Fungal endocarditis caused by Pseudallescheria (Petriellidium) boydii in an intravenous drug abuser.一名静脉注射吸毒者患波氏假阿利什菌（皮氏瓶霉）所致真菌性心内膜炎。
Tex Heart Inst J. 1987 Sep;14(3):321-4.
2
Successful treatment of simultaneous pulmonary Pseudallescheria boydii and Aspergillus terreus infection with oral itraconazole.口服伊曲康唑成功治疗同时发生的波氏假阿利什菌和土曲霉肺部感染。
Clin Infect Dis. 1993 Jun;16(6):803-5. doi: 10.1093/clind/16.6.803.
3
Comparative and collaborative evaluation of standardization of antifungal susceptibility testing for filamentous fungi.丝状真菌抗真菌药敏试验标准化的比较与协作评估
Antimicrob Agents Chemother. 1995 Feb;39(2):314-9. doi: 10.1128/AAC.39.2.314.
4
Near-drowning complicated by brain abscess due to Petriellidium boydii.博伊德佩特里盘菌所致脑脓肿并发的近乎溺水
Arch Neurol. 1982 Aug;39(8):511-3. doi: 10.1001/archneur.1982.00510200053011.
5
Pseudallescheria boydii infections treated with ketoconazole. Clinical evaluations of seven patients and in vitro susceptibility results.酮康唑治疗波氏假阿利什菌感染。7例患者的临床评估及体外药敏结果。
Chest. 1984 Aug;86(2):219-24. doi: 10.1378/chest.86.2.219.
6
Brain abscesses due to Pseudallescheria boydii associated with primary non-Hodgkin's lymphoma of the central nervous system: a case report and literature review.
Rev Infect Dis. 1985 Mar-Apr;7(2):272-77. doi: 10.1093/clinids/7.2.272.
7
The effect of ketoconazole on amphotericin B in a model of disseminated aspergillosis.酮康唑在播散性曲霉病模型中对两性霉素B的影响。
J Infect Dis. 1985 May;151(5):902-10. doi: 10.1093/infdis/151.5.902.
8
Clinical significance of Pseudallescheria boydii: a review of 10 years' experience.波氏假阿利什菌的临床意义：十年经验回顾
Mayo Clin Proc. 1985 Aug;60(8):531-7. doi: 10.1016/s0025-6196(12)60571-0.
9
Pseudallescheria boydii infection of the central nervous system in a cardiac transplant recipient.
South Med J. 1986 Mar;79(3):383-4. doi: 10.1097/00007611-198603000-00034.
10
Pseudallescheria boydii brain abscess. Complication of an intravenous catheter.波氏假阿利什霉脑脓肿。静脉导管并发症。
Am J Med. 1988 Feb;84(2):359-62. doi: 10.1016/0002-9343(88)90441-x.