两性霉素B和抗真菌唑类单独及联合使用对波氏假阿利什菌的活性。
Activities of amphotericin B and antifungal azoles alone and in combination against Pseudallescheria boydii.
作者信息
Walsh T J, Peter J, McGough D A, Fothergill A W, Rinaldi M G, Pizzo P A
机构信息
Infectious Diseases Section, National Cancer Institute, Bethesda, Maryland, USA.
出版信息
Antimicrob Agents Chemother. 1995 Jun;39(6):1361-4. doi: 10.1128/AAC.39.6.1361.
Abstract
In order to develop new approaches to treatment of infections due to Pseudallescheria boydii, the in vitro antifungal activity of amphotericin B alone and in combination with miconazole, itraconazole, and fluconazole was studied. Combinations of amphotericin B and antifungal azoles were synergistic, additive, or indifferent in their interaction against P. boydii. Antagonism was not observed.
摘要
为了开发治疗波氏假阿利什菌感染的新方法，研究了两性霉素B单独以及与咪康唑、伊曲康唑和氟康唑联合使用时的体外抗真菌活性。两性霉素B与抗真菌唑类药物联合使用时，在抗波氏假阿利什菌的相互作用中表现为协同、相加或无相互作用。未观察到拮抗作用。
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