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苦玄参酸通过细胞周期阻滞、ROS 产生和靶向 mTOR/PI3K/AKT 信号通路诱导顺铂耐药人宫颈癌细胞的抗癌作用。

Tormentic acid induces anticancer effects in cisplatin-resistant human cervical cancer cells mediated via cell cycle arrest, ROS production, and targeting mTOR/PI3K/AKT signalling pathway.

机构信息

Department of Oncology, Second Hospital of Shanxi Medical University, Taiyuan, Shanxi 030000, China.

出版信息

J BUON. 2021 Mar-Apr;26(2):643.

PMID:34077027
Abstract

The Editors of JBUON issue an Expression of Concern to 'Tormentic acid induces anticancer effects in cisplatin-resistant human cervical cancer cells mediated via cell cycle arrest, ROS production, and targeting mTOR/PI3K/AKT signalling pathway', by Jinrong Wu, Ning Wang, Gang Jin, Lili Xue, JBUON 2020;25(1):74-79; PMID: 32277616. Following the publication of the above article, readers drew to our attention that part of the data was possibly unreliable. We sent emails to the authors with a request to provide the raw data to prove the originality, but received no reply. Therefore, as we continue to work through the issues raised, we advise readers to interpret the information presented in the article with due caution. We thank the readers for bringing this matter to our attention. We apologize for any inconvenience it may cause.

摘要

JBUON 杂志编辑就“柠檬酸通过细胞周期阻滞、ROS 产生和靶向 mTOR/PI3K/AKT 信号通路诱导顺铂耐药人宫颈癌细胞的抗癌作用”一文表达关注,作者:Jinrong Wu、Ning Wang、Gang Jin、Lili Xue,JBUON 2020;25(1):74-79;PMID:32277616。在发表上述文章后,读者提请我们注意部分数据可能不可靠。我们向作者发送电子邮件,要求提供原始数据以证明其原创性,但未收到回复。因此,在我们继续解决所提出的问题时,我们建议读者谨慎解读该文章中的信息。感谢读者提出此事,我们对由此带来的不便表示歉意。

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