COVID-19 的新兴骨代谢表型：临床和病理生理方面。
The emerging osteo-metabolic phenotype of COVID-19: clinical and pathophysiological aspects.
机构信息
Institute of Endocrine and Metabolic Sciences, Vita-Salute San Raffaele University, IRCCS San Raffaele Hospital, Milan, Italy.
出版信息
Nat Rev Endocrinol. 2021 Aug;17(8):445-446. doi: 10.1038/s41574-021-00516-y.
Abstract
An emerging feature of COVID-19 is a clinically relevant osteo-metabolic phenotype characterized by widespread acute hypocalcaemia and chronic hypovitaminosis D with high prevalence of vertebral fractures. This phenotype might have negative effects on disease severity and its components could represent possible targets for prevention of SARS-CoV-2 infection and poor COVID-19 outcomes.
摘要
COVID-19 的一个新出现特征是一种具有临床意义的骨代谢表型，其特征为广泛的急性低钙血症和慢性维生素 D 缺乏症，且椎体骨折的患病率很高。这种表型可能对疾病严重程度有负面影响，其组成部分可能是预防 SARS-CoV-2 感染和 COVID-19 不良结局的潜在靶点。
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本文引用的文献
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Rev Endocr Metab Disord. 2022 Apr;23(2):299-308. doi: 10.1007/s11154-021-09655-z. Epub 2021 Apr 13.
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