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针对免疫代谢进行靶向治疗是否可以控制 COVID-19 感染的负担?

Could targeting immunometabolism be a way to control the burden of COVID-19 infection?

机构信息

Department of Biomedical and Diagnostic Sciences, College of Veterinary Medicine, The University of Tennessee, Knoxville, TN, USA; Department of Virology, Faculty of Veterinary Medicine, Erciyes University, Kayseri, TR, Turkey.

Department of Biomedical and Diagnostic Sciences, College of Veterinary Medicine, The University of Tennessee, Knoxville, TN, USA.

出版信息

Microbes Infect. 2021 Mar-Apr;23(2-3):104780. doi: 10.1016/j.micinf.2021.104780. Epub 2021 Jan 20.

Abstract

This review portrays the metabolic consequences of Covid-19 infection at different stages of the clinical syndrome. It also describes how events can change when patients with metabolic problems are infected and the effects that diet and nutrition might play to influence the outcome of infection. We also discuss the types of maneuvers that could be used to reshape metabolic events and question if this approach could be a practical therapy used alone or in combination with other approaches to reduce the burden of Covid-19 infection.

摘要

这篇综述描绘了新冠病毒感染在临床综合征不同阶段的代谢后果。它还描述了当代谢问题患者感染时情况如何变化,以及饮食和营养可能发挥的作用来影响感染的结果。我们还讨论了可以用来重塑代谢事件的各种方法,并质疑这种方法是否可以作为一种单独使用或与其他方法结合使用以减轻新冠病毒感染负担的实用疗法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3074/7816601/5a95c071c237/gr1_lrg.jpg

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