Zhang Li, Liu Minjie, Li Jianying, Li Xiaoli, Cheng Li, Ji Yahong, Li Na, Wang Junning
Department of Intensive Care Unit, Honghui Hospital, Xi'an Jiaotong University, Xi'an, Shaanxi, 710054, People's Republic of China.
Xi'an Public Health Center, Xi'an, Shaanxi, 710200, People's Republic of China.
Int J Gen Med. 2021 May 25;14:2069-2078. doi: 10.2147/IJGM.S315159. eCollection 2021.
Effective management of foreign-imported COVID-19 cases is a new and great challenge for China. Our study focused on the foreign-imported COVID-19 cases to provide detailed data for insights into the prevention, early diagnosis, treatment and control of imported COVID-19.
For this observational and retrospective study, we investigated the clinical characteristics of imported COVID-19 cases that were confirmed by real-time RT-PCR in the Xi'an Public Health Center from 29 March 2020 to 31 August 2020.
Of the 79 patients with COVID-19, 19 (24.1%) had exposure to confirmed COVID-19 patients, 15 (19.0%) had exposure to suspicious COVID-19 patients, and 45 (56.9%) had an unclear history of exposure to confirmed patients. The mean age of the patients was 38 years, and 70 (88.7%) patients were male. Except for 2 severe cases, the remaining 58 (73.4%) cases displayed mild or moderate symptoms, and 19 (24.2%) infected patients were asymptomatic. Twenty-one (26.6%) patients were not diagnosed until a third or later nucleic acid test. Ten (12.7%) patients had chronic diseases. The most common manifestations of the patients were cough [18 (22.8%) cases], fever [9 (11.4%) cases] and sore throat [9 (11.4%) cases]. Forty-one (51.9%) cases showed abnormal chest CT images, To date, all patients have been discharged, and no patient has died.
The imported COVID-19 cases in Xi'an were mainly young and middle-aged adults with mild or moderate symptoms who had a low rate of comorbidity, showed favourable laboratory and chest CT images, and had a better prognosis. Notably, for suspected COVID-19 cases, at least three consecutive nucleic acid tests should be carried out to avoid missed detection of infected patients. Except for severe cases, high-level medical resources are not necessary in most cases.
有效管理境外输入性新型冠状病毒肺炎（COVID-19）病例对中国来说是一项全新的巨大挑战。我们的研究聚焦于境外输入性COVID-19病例，旨在提供详细数据，以深入了解输入性COVID-19的预防、早期诊断、治疗及防控情况。
在这项观察性回顾研究中，我们调查了2020年3月29日至2020年8月31日在西安市公共卫生中心经实时逆转录聚合酶链反应（RT-PCR）确诊的境外输入性COVID-19病例的临床特征。
79例COVID-19患者中，19例（24.1%）曾接触确诊COVID-19患者，15例（19.0%）曾接触疑似COVID-19患者，45例（56.9%）接触确诊患者的暴露史不明。患者的平均年龄为38岁，70例（88.7%）为男性。除2例重症病例外，其余58例（73.4%）表现为轻症或中症，19例（24.2%）感染患者无症状。21例（26.6%）患者直到第三次或更晚的核酸检测时才被确诊。10例（12.7%）患者患有慢性病。患者最常见的表现为咳嗽[18例（22.8%）]、发热[9例（11.4%）]和咽痛[9例（11.4%）]。41例（51.9%）病例胸部CT图像异常。截至目前，所有患者均已出院，无死亡病例。
西安市境外输入性COVID-19病例主要为中青年，症状以轻症或中症为主，合并症发生率低，实验室检查及胸部CT图像表现良好，预后较好。值得注意的是，对于疑似COVID-19病例，应至少连续进行三次核酸检测，以避免漏诊感染患者。除重症病例外，多数情况下无需高级别医疗资源。
