Serra Raffaele, Abramo Andrea, Ielapi Nicola, Procopio Salvatore, Marino Pietro
Interuniversity Center of Phlebolymphology (CIFL), International Research and Educational Program in Clinical and Experimental Biotechnology, Department of Surgical and Medical Sciences, University Magna Graecia of Catanzaro, Catanzaro, Italy.
Department of Medical and Surgical Sciences, University Magna Graecia of Catanzaro, Catanzaro, Italy.
Risk Manag Healthc Policy. 2021 May 27;14:2181-2190. doi: 10.2147/RMHP.S307150. eCollection 2021.
Peripheral artery disease (PAD) of the lower limbs represents one of the most important clinical conditions among vascular disease and can negatively impact quality of life of affected patients, representing also an important socioeconomic burden. Several risk factors predispose to PAD and its complications. Nevertheless, the role of pollution in this context has not been fully evaluated and this article explored the most updated information on epidemiology and environmental pollution in order to hypothesize the possible contribution of air pollution in the onset of PAD. Pollution is an important problem for the global community and has harmful effects on human health and cardiovascular system, and, specifically, particulate matter 10 (PM) was found significantly associated with PAD.
下肢外周动脉疾病（PAD）是血管疾病中最重要的临床病症之一，会对患病患者的生活质量产生负面影响，也是一项重大的社会经济负担。有多种风险因素易引发PAD及其并发症。然而，污染在此背景下的作用尚未得到充分评估，本文探讨了有关流行病学和环境污染的最新信息，以便推测空气污染在PAD发病过程中可能起到的作用。污染是全球社会面临的一个重要问题，对人类健康和心血管系统具有有害影响，具体而言，已发现可吸入颗粒物10（PM）与PAD显著相关。
