Larson Anthony S, Lehman Vance T, Savastano Luis E, Lanzino Giuseppe, Campeau Norbert G, Welker Kirk M, Klaas James P
Department of Radiology, Mayo Clinic, Rochester, MN, United States.
Department of Neurosurgery, Mayo Clinic, Rochester, MN, United States.
Front Neurol. 2021 May 17;12:662393. doi: 10.3389/fneur.2021.662393. eCollection 2021.
Moyamoya disease (MMD) is a complex and incompletely-understood cerebrovascular pathological entity that requires thorough clinical and imaging evaluation. Moyamoya is rare, thereby making the establishment of an effective, thorough and interdisciplinary patient evaluation protocol challenging, even within specialized referral centers. Nevertheless, implementation of such a protocol is crucial in order to provide the best possible evaluation and treatment for MMD patients. Here, we describe our institution's implementation of, rationale for, and experience with a comprehensive multidisciplinary collaboration and evaluation strategy for adult patients with moyamoya. This evaluation course consists of, first of all, a thorough clinical and laboratory evaluation with a vascular neurologist. This is followed by a comprehensive imaging assessment which evaluates angiographic and parenchymal features, in addition to cerebrovascular functionality. Finally, appropriate referrals are made to consulting services as indicated, which includes vascular neurosurgery. These steps are described in detail herein.
烟雾病（MMD）是一种复杂且尚未完全被理解的脑血管病理实体，需要进行全面的临床和影像学评估。烟雾病较为罕见，因此即使在专业转诊中心，建立一套有效、全面且跨学科的患者评估方案也具有挑战性。然而，实施这样一套方案对于为烟雾病患者提供尽可能最佳的评估和治疗至关重要。在此，我们描述了我们机构针对成年烟雾病患者实施的全面多学科协作与评估策略、其基本原理及经验。这个评估过程首先包括由血管神经科医生进行全面的临床和实验室评估。随后是全面的影像学评估，除了脑血管功能外，还评估血管造影和实质特征。最后，根据需要向包括血管神经外科在内的咨询服务部门进行适当转诊。本文将详细描述这些步骤。
