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酷似路易体痴呆自主神经功能障碍的病态窦房结综合征

Sick Sinus Syndrome Mimicking Autonomic Dysfunction of Dementia With Lewy Bodies.

作者信息

Sawagashira Ryo, Sasagawa Yoshihisa, Matsukura Mayumi, Takamaru Yuji

机构信息

Physiology, Hokkaido University, Sapporo, JPN.

Psychiatry, Hokkaido University, Sapporo, JPN.

出版信息

Cureus. 2021 Apr 24;13(4):e14667. doi: 10.7759/cureus.14667.

DOI:10.7759/cureus.14667
PMID:34079668
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8159329/
Abstract

Dementia with Lewy bodies (DLB) is recognized as the second most common form of dementia in aged people. It is well known that patients with DLB often develop various autonomic symptoms. Here, we present a case in which there was sick sinus syndrome mimicking the DLB-related autonomic dysfunctions. After the pacemaker implantation, the patient's symptom perfectly extinguished.It is essential for psychiatrists or other professionals who are mainly seeing dementia patients to rule out critical causes that may mimic autonomic symptoms in patients with DLB.

摘要

路易体痴呆(DLB)被认为是老年人中第二常见的痴呆形式。众所周知,DLB患者常出现各种自主神经症状。在此,我们报告一例疑似与DLB相关自主神经功能障碍的病态窦房结综合征病例。起搏器植入后,患者症状完全消失。对于主要诊治痴呆患者的精神科医生或其他专业人员来说,排除可能模仿DLB患者自主神经症状的关键病因至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b330/8159329/ac756d13a7ce/cureus-0013-00000014667-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b330/8159329/ac756d13a7ce/cureus-0013-00000014667-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b330/8159329/ac756d13a7ce/cureus-0013-00000014667-i01.jpg

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引用本文的文献

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Sick sinus syndrome and high-degree atrioventricular block in dementia with Lewy bodies and other dementia subtypes: A study of ≈ 73,000 patients with dementia.路易体痴呆及其他痴呆亚型中的病态窦房结综合征和高度房室传导阻滞:一项对约73000例痴呆患者的研究
Alzheimers Dement (N Y). 2025 Feb 19;11(1):e70053. doi: 10.1002/trc2.70053. eCollection 2025 Jan-Mar.
2
High prevalence of atrial conduction abnormalities in Lewy body disease - a marker of cardiac complications?路易体病中心房传导异常的高患病率——心脏并发症的一个标志物?
Geroscience. 2025 Jan 10. doi: 10.1007/s11357-024-01479-4.
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Exploring the prevalence of undetected bradyarrhythmia in dementia with Lewy bodies.

本文引用的文献

1
Diagnosis and management of dementia with Lewy bodies: Fourth consensus report of the DLB Consortium.路易体痴呆的诊断与管理:DLB联盟第四次共识报告
Neurology. 2017 Jul 4;89(1):88-100. doi: 10.1212/WNL.0000000000004058. Epub 2017 Jun 7.
2
Delirium and dementia with Lewy bodies: distinct diagnoses or part of the same spectrum?路易体痴呆伴意识障碍:不同的诊断还是同一谱系的一部分?
J Neurol Neurosurg Psychiatry. 2015 Jan;86(1):50-9. doi: 10.1136/jnnp-2013-306389. Epub 2014 May 23.
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Sick sinus syndrome: a review.病态窦房结综合征:综述。
探讨路易体痴呆中未被发现的缓慢性心律失常的患病率。
Clin Auton Res. 2023 Aug;33(4):433-442. doi: 10.1007/s10286-023-00962-w. Epub 2023 Jul 5.
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Pacemaker Implants and Their Influence on the Daily Life of Patients with Dementia with Lewy Bodies: A Qualitative Case Study.心脏起搏器植入及其对路易体痴呆患者日常生活的影响:一项定性案例研究。
Neurol Ther. 2023 Aug;12(4):1359-1373. doi: 10.1007/s40120-023-00513-5. Epub 2023 Jun 16.
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Dementia with Lewy bodies.路易体痴呆
Dialogues Clin Neurosci. 2004 Sep;6(3):333-41. doi: 10.31887/DCNS.2004.6.3/imckeith.
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Complete atrioventricular block and ventricular tachyarrhythmia associated with donepezil.与多奈哌齐相关的完全性房室传导阻滞和室性快速性心律失常。
Emerg Med J. 2006 Aug;23(8):641-2. doi: 10.1136/emj.2006.036251.