Sakai Y, Takayanagi K, Inoue T, Yamaguchi H, Hayashi T, Morooka S, Takabatake Y, Sato Y
Department of Cardiology, Koshigaya Hospital, Dokkyo University School of Medicine, Saitama, Japan.
Angiology. 1988 Jul;39(7 Pt 1):625-30. doi: 10.1177/000331978803900711.
Multiple coronary artery aneurysms, rarely seen in patients with atherosclerotic heart disease, can be frequently observed in children with Kawasaki disease. However, their long-term clinical courses still remain obscure. A thirty-nine-year-old male came to our clinic because of congestive heart failure. A left ventriculogram revealed highly reduced wall motion. A coronary angiogram showed left main trunk aneurysm with complete occlusion of the left anterior descending artery and ramification of the right coronary artery close to the ostium. Six months after discharge, he died suddenly. On autopsy, aneurysms were observed in the left main trunk and right coronary artery, together with an old anteroseptal myocardial infarction. Although he did not have a clear history of febrile disease in childhood, he was highly suspected to be a long-term survivor of Kawasaki disease because of the unique form and distribution of the coronary artery aneurysms.
多发性冠状动脉瘤在动脉粥样硬化性心脏病患者中很少见,但在川崎病患儿中却经常可以观察到。然而,它们的长期临床病程仍不明确。一名39岁男性因充血性心力衰竭前来我院就诊。左心室造影显示室壁运动明显减弱。冠状动脉造影显示左主干动脉瘤,左前降支完全闭塞,右冠状动脉开口附近分支。出院6个月后,他突然死亡。尸检发现左主干和右冠状动脉有动脉瘤,同时伴有陈旧性前间隔心肌梗死。尽管他童年时没有明确的发热病史,但由于冠状动脉瘤的独特形态和分布,高度怀疑他是川崎病的长期存活者。