Vrancken L, Lejeune M, Pirotte M, Duray E, Köse M, Beguin Y, Caers J
Service d'Hématologie, CHU Liège, Belgique ; Laboratoire d'Hématologie, GIGA-I³, ULiège, Belgique.
Rev Med Liege. 2021 May;76(5-6):482-487.
Multiple myeloma is the second most common hematological malignancy, characterized by an uncontrollable proliferation of clonal plasma cells. Although progresses in understanding its pathobiology and its treatment are made every day, it remains incurable. Since myeloma is more and more common, especially in the elderly, we would like to propose an overview of its pathobiology, diagnostic criteria and treatment «guidelines».
多发性骨髓瘤是第二常见的血液系统恶性肿瘤,其特征为克隆性浆细胞的失控性增殖。尽管对其病理生物学及治疗的认识每天都在进步,但它仍然无法治愈。由于骨髓瘤越来越常见,尤其是在老年人中,我们想对其病理生物学、诊断标准及治疗“指南”做一概述。