Arlandis Salvador, Bonillo Miguel Ángel, Franco Agustín, Peri Lluis, González-López Raquel, Martínez-Cuenca Esther, Romero Antonio, Müller-Arteaga Carlos, García-Matres María Justa
Hospital Universitario y Politécnico La Fe. Valencia. España.
Hospital Universitario Clínic. Barcelona. España.
Arch Esp Urol. 2021 Jun;74(5):459-469.
To study the use and results of cystoscopy and bladder hydrodistension in the objective assessment of patients with Bladder Pain Syndrome (BPS), in routine clinical practice.
Observational, non-interventional, national, multicenter study carried out in Functional Urology and Urodynamic Units of Spain belonging to the IFU Group. 273 women with BPS who underwent cystoscopy at baseline as a diagnostic tool according to clinical criteria and following the routine clinical practice of each center, were studied. The pre and post hydrodistension findings and the scores of the symptom and Health-Related Quality of Life (HRQoL) questionnaires were described: BPIC-SS, PPBC, PGI-S and EQ-5D-5L.
The mean age (SD) was 59 (14) years with a high presence of bladder symptoms: increased voiding frequency (81.7%), nocturia (74%) and urgency (60.4%). 40.7% of cystoscopies were performed under anesthesia and 73.7% uses a standard rigid cystoscope. Hunner lesions were observed in 9.9% of the patients, hypervascularizations (46.2%), glomerulations (23.4%), mild bleeding (6.6%) and scars (2.2%). After hydrodistension, a greater number of grade 1 and 2 lesions were observed. In 51.6% of the patients there were no changes, but in 27.5% slight changes were observed and in 11.4% moderate or severe changes. Symptom and HRQoL questionnaire scores showed no association with cystoscopy findings before and after hydrodistension.
The value of the cystoscopic findings in the SDV has yet to be defined, although it plays a fundamental role in the differential diagnosis. In this observational study, we did not find a correlation of the cystoscopic findings with the symptoms of the patients, measured by validated questionnaires, nor with the HRQoL.
在常规临床实践中，研究膀胱镜检查和膀胱水扩张术在膀胱疼痛综合征（BPS）患者客观评估中的应用及结果。
在西班牙属于IFU集团的功能性泌尿外科和尿动力学单位开展的一项观察性、非干预性、全国性、多中心研究。研究了273例根据临床标准并按照各中心常规临床实践在基线时接受膀胱镜检查作为诊断工具的BPS女性患者。描述了水扩张前后的检查结果以及症状和健康相关生活质量（HRQoL）问卷的得分：BPIC - SS、PPBC、PGI - S和EQ - 5D - 5L。
平均年龄（标准差）为59（14）岁，膀胱症状普遍存在：排尿频率增加（81.7%）、夜尿症（74%）和尿急（60.4%）。40.7%的膀胱镜检查在麻醉下进行，73.7%使用标准硬性膀胱镜。9.9%的患者观察到Hunner病变，46.2%有血管增生，23.4%有小球状出血，6.6%有轻度出血，2.2%有瘢痕。水扩张后，观察到更多的1级和2级病变。51.6%的患者没有变化，但27.5%观察到轻微变化，11.4%观察到中度或重度变化。症状和HRQoL问卷得分在水扩张前后与膀胱镜检查结果均无关联。
膀胱镜检查结果在膀胱疼痛综合征中的价值尚未明确，尽管其在鉴别诊断中起重要作用。在这项观察性研究中，我们未发现通过有效问卷测量的膀胱镜检查结果与患者症状之间以及与健康相关生活质量之间存在相关性。
