Yu Wan-Ru, Jiang Yuan-Hong, Jhang Jia-Fong, Kuo Hann-Chorng
Department of Nursing, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan.
Institute of Medical Sciences, Tzu Chi University, Hualien, Taiwan.
Tzu Chi Med J. 2023 Aug 22;36(1):30-37. doi: 10.4103/tcmj.tcmj_172_23. eCollection 2024 Jan-Mar.
Interstitial cystitis/bladder pain syndrome (IC/BPS) is a chronic inflammatory bladder disease of unknown etiology, characterized by bladder pain and frequency urgency symptoms. Based on the cystoscopic findings after hydrodistention under anesthesia, the phenotype of IC/BPS includes no glamerulation, characteristic glomerulation, and with Hunner's lesion. IC is specifically defined if there are characteristic Hunner's lesion appeared in cystoscopy or after hydrodistention. If there are glomerulations without Hunner's lesion, BPS should be considered. The definition of Hunner's lesion and glomerulations differs based on different definition and observations. Currently, there has been no clear description and grading of the glomerulations and Hunner's lesion. Because the classification of IC/BPS has an impact on the treatment strategy and associated with therapeutic outcome, it is unmet to have a clear definition and consensus on the characteristic cystoscopic findings of IC/BPS. This article reviews the literature and presents the figures of Hunner's lesions and description of different mucosal lesions after cystoscopic hydrodistention.
间质性膀胱炎/膀胱疼痛综合征(IC/BPS)是一种病因不明的慢性炎症性膀胱疾病,其特征为膀胱疼痛和尿频尿急症状。根据麻醉下水扩张术后的膀胱镜检查结果,IC/BPS的表型包括无点状出血、典型点状出血以及存在Hunner病变。如果膀胱镜检查或水扩张术后出现典型的Hunner病变,则明确诊断为IC。如果存在无Hunner病变的点状出血,则应考虑诊断为BPS。Hunner病变和点状出血的定义因不同的定义和观察而异。目前,对于点状出血和Hunner病变尚无明确的描述和分级。由于IC/BPS的分类对治疗策略有影响且与治疗结果相关,因此对IC/BPS特征性膀胱镜检查结果有明确的定义并达成共识仍未实现。本文回顾了相关文献,并展示了Hunner病变的图片以及膀胱镜下水扩张术后不同黏膜病变的描述。