产色葡萄球菌ATCC 43764的基因组序列草图，一株具有抗菌潜力的凝固酶阴性葡萄球菌菌株
Draft Genome Sequence of Staphylococcus chromogenes ATCC 43764, a Coagulase-Negative Staphylococcus Strain with Antibacterial Potential.
作者信息
Chin Denny, Deecker Shayna R, Ensminger Alexander W, Heinrichs David E
机构信息
Department of Microbiology and Immunology, University of Western Ontario, London, Ontario, Canada.
Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada.
出版信息
Microbiol Resour Announc. 2021 Jun 3;10(22):e0049221. doi: 10.1128/MRA.00492-21.
Abstract
Staphylococcus chromogenes can cause subclinical mastitis in cows, and some strains have also demonstrated antibacterial activity against pathogens such as methicillin-resistant Staphylococcus aureus (MRSA). Here, we report the draft genome sequence of the type strain ATCC 43764, which secretes the prodrug 6-thioguanine (6-TG), which antagonizes MRSA virulence.
摘要
产色葡萄球菌可引起奶牛的亚临床乳腺炎，并且一些菌株还对诸如耐甲氧西林金黄色葡萄球菌（MRSA）等病原体表现出抗菌活性。在此，我们报告了模式菌株ATCC 43764的基因组草图序列，该菌株分泌前药6-硫鸟嘌呤（6-TG），其可拮抗MRSA的毒力。
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