ImageJ 软件在类风湿关节炎患者手关节间隙变窄定量分析中的应用。
Application of ImageJ Software for the Quantification of Hand Joint Space Narrowing in Patients with Rheumatoid Arthritis.
机构信息
Department of Rheumatology, Military Hospital 103, Hanoi, Vietnam.
Vietnam Military Medical University, Hanoi, Vietnam.
出版信息
Curr Rheumatol Rev. 2022;18(2):136-143. doi: 10.2174/1573397117666210602113848.
BACKGROUND
ImageJ software is used to quantify the joint space width (JSW) of hand and wrist in patients with rheumatoid arthritis (RA) as well as in the healthy control group.
METHODS
Forty-one RA patients and 31 healthy controls were included in this study. All of 72 participants underwent digital radiography of the bilateral hand and wrist; then, all the images were opened by ImageJ software to measure the width of wrist and hand joint space (total 2160 joints). Joint space narrowing (JSN) was defined if the width was less than the mean - 2SD of the control group.
RESULT
The mean JSW of all sites of wrist and hand joints of RA patients were significantly reduced as compared to those in the control group (p<0.001). There were 37/41 (90.24%) RA patients who had JSN in at least one joint in hand or wrist. In total, 70.89% of joints on the right and 68.46% of joints on the left wrist and hand had JSN.
CONCLUSION
ImageJ software is simple and convenient that helps rheumatologists quantify the width of joint space for diagnosis and follow-up in RA patients.
背景
ImageJ 软件可用于量化类风湿关节炎 (RA) 患者和健康对照组的手部和腕部关节间隙宽度 (JSW)。
方法
本研究纳入了 41 例 RA 患者和 31 例健康对照者。所有 72 名参与者均接受了双侧手部和腕部数字 X 线摄影；然后，所有图像均由 ImageJ 软件打开以测量腕关节和手部关节间隙的宽度（共 2160 个关节）。如果宽度小于对照组的平均值-2SD，则定义为关节间隙变窄 (JSN)。
结果
与对照组相比，RA 患者手部和腕部所有关节的平均 JSW 均显著降低 (p<0.001)。37/41 (90.24%) 的 RA 患者至少有一个手部或腕部关节存在 JSN。右腕和手总共 70.89%的关节和左腕和手 68.46%的关节存在 JSN。
结论
ImageJ 软件简单方便，有助于风湿病学家量化 RA 患者的关节间隙宽度，用于诊断和随访。
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