推进拉曼光谱学从研究到临床应用：转化的潜力和挑战。
Advancing Raman spectroscopy from research to clinic: Translational potential and challenges.
机构信息
Department of Mechanical Engineering, Johns Hopkins University, Baltimore, MD 21218, United States.
Department of Botany, School of Life Sciences, Mahatma Gandhi Central University, Motihari, Bihar 845401, India.
出版信息
Spectrochim Acta A Mol Biomol Spectrosc. 2021 Nov 5;260:119957. doi: 10.1016/j.saa.2021.119957. Epub 2021 May 13.
Raman spectroscopy has emerged as a non-invasive and versatile diagnostic technique due to its ability to provide molecule-specific information with ultrahigh sensitivity at near-physiological conditions. Despite exhibiting substantial potential, its translation from optical bench to clinical settings has been impacted by associated limitations. This perspective discusses recent clinical and biomedical applications of Raman spectroscopy and technological advancements that provide valuable insights and encouragement for resolving some of the most challenging hurdles.
拉曼光谱技术由于能够在接近生理条件下提供具有超高灵敏度的分子特异性信息，已成为一种非侵入性且多功能的诊断技术。尽管该技术具有巨大的潜力，但它从光学平台到临床应用的转化受到了相关限制的影响。本文讨论了拉曼光谱的最新临床和生物医学应用以及技术进展，这些进展为解决一些最具挑战性的难题提供了有价值的见解和鼓励。
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