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[大鼠个体发育过程中胃黏膜腺上皮的细胞分化]

[Cytodifferentiation of the epithelium of the gastric mucosa glands of rats in ontogenesis].

作者信息

Odintsova I A

出版信息

Arkh Anat Gistol Embriol. 1988 Apr;94(4):48-56.

PMID:3408355
Abstract

Structure of epithelium in the mucous membrane glands of the rat stomach has been studied electron microscopically during embryonal and postnatal periods of development. Time of initial appearance of various types of cells in early stages of the gastric epithelium histogenesis has been verified. Asynchronity of their appearance is demonstrated. In epithelium of the gastric glands in 20-day-old rat embryos poorly differentiated exocrine and also endocrine D- and G-cells are revealed. On the 1st day EC-, ECl-, and on the 3d day--X-endocrinocytes appear. Neighbouring exocrinocytes connect with each other by means of both nonspecific and specific intercellular contacts. Exocrine and endocrine cells connect by means of desmosomes. For the animals of each age group certain range of ultrastructural organization in variously differentiated glandulocytes (they are morphological basis of the reactive changes) is specific.

摘要

在大鼠胃黏膜腺上皮的胚胎期和出生后发育阶段,利用电子显微镜对其结构进行了研究。已证实胃上皮组织发生早期各种类型细胞的最初出现时间。结果表明它们的出现具有异步性。在20日龄大鼠胚胎的胃腺上皮中,发现了分化不良的外分泌细胞以及内分泌D细胞和G细胞。在出生后第1天出现EC细胞、ECl细胞,在第3天出现X内分泌细胞。相邻的外分泌细胞通过非特异性和特异性细胞间连接相互连接。外分泌细胞和内分泌细胞通过桥粒连接。对于每个年龄组的动物,不同分化程度的腺细胞(它们是反应性变化的形态学基础)具有特定范围的超微结构组织。

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