氯氮平诱发22q11.2缺失综合征患者的胃食管反流。一例胃食管副作用管理病例报告，未放弃氯氮平的有效性。
Clozapine-induced gastroesophageal rumination in 22q11.2 Deletion Syndrome. A case report on gastroesophageal side effects management without renouncing clozapine's effectiveness.
作者信息
Accinni Tommaso, Frascarelli Marianna, Ghezzi Francesco, Panzera Alessia, Buzzanca Antonino, Fanella Martina, Di Bonaventura Carlo, Carlone Luca, Girardi Nicoletta, Pasquini Massimo, Di Fabio Fabio
机构信息
Department of Human Neurosciences Sapienza University Rome Italy.
出版信息
Clin Case Rep. 2021 May 24;9(5):e04134. doi: 10.1002/ccr3.4134. eCollection 2021 May.
Abstract
Despite entailing more severe and uncommon side effects in 22q11.2DS compared to idiopathic schizophrenia, we strongly believe that clozapine should continue to be considered the gold standard for all treatment-resistant schizophrenia, even in 22qDS.
摘要
尽管与特发性精神分裂症相比，22q11.2缺失综合征（22q11.2DS）会引发更严重且罕见的副作用，但我们坚信，氯氮平仍应继续被视为所有难治性精神分裂症的金标准治疗药物，即便对于22q11.2缺失综合征患者亦是如此。
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