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一名患有先天性腿部巨大症患者的异位骨化中的骨髓炎。

Osteomyelitis in heterotopic ossification in a patient with congenital gigantism of the leg.

作者信息

Galea Wismayer Martina, Sant Kurstein, Giordmaina Ryan, McNally Martin

机构信息

Department of Trauma and Orthopaedics, Mater Dei Hospital, Msida, Malta.

The Oxford Bone Infection Unit, Nuffield Orthopaedic Centre, Oxford University Hospitals, UK.

出版信息

J Bone Jt Infect. 2021 Apr 16;6(5):141-145. doi: 10.5194/jbji-6-141-2021. eCollection 2021.

DOI:10.5194/jbji-6-141-2021
PMID:34084703
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8131960/
Abstract

This paper presents the first report of osteomyelitis in heterotopic ossification in a patient with macrodystrophia lipomatosa. Careful review of magnetic resonance imaging allowed correct diagnosis and design of a limited surgical excision. Osteomyelitis should be considered in the differential diagnosis of pain and discharge when heterotopic ossification is present.

摘要

本文首次报道了巨脂性营养障碍患者异位骨化合并骨髓炎的病例。仔细审查磁共振成像有助于做出正确诊断并设计有限的手术切除方案。当存在异位骨化时，在疼痛和引流的鉴别诊断中应考虑骨髓炎。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98b0/8131960/72878a960205/jbji-6-141-g05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98b0/8131960/a15e285d0342/jbji-6-141-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98b0/8131960/3db790c91d9f/jbji-6-141-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98b0/8131960/55dc5c2dd2ec/jbji-6-141-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98b0/8131960/c8d82d2d171a/jbji-6-141-g04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98b0/8131960/72878a960205/jbji-6-141-g05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98b0/8131960/a15e285d0342/jbji-6-141-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98b0/8131960/3db790c91d9f/jbji-6-141-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98b0/8131960/55dc5c2dd2ec/jbji-6-141-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98b0/8131960/c8d82d2d171a/jbji-6-141-g04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98b0/8131960/72878a960205/jbji-6-141-g05.jpg

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引用本文的文献

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Occult lipomatosis of the nerve as part of macrodystrophia lipomatosa: illustrative case.神经隐匿性脂肪瘤病作为巨脂性营养障碍的一部分：病例说明
J Neurosurg Case Lessons. 2023 Jan 9;5(2). doi: 10.3171/CASE22463.

本文引用的文献

1
Heterotopic Ossification in Orthopaedic and Trauma surgery: A Histopathological Ossification Score.骨科和创伤外科中的异位骨化：组织病理学骨化评分。
Sci Rep. 2019 Dec 5;9(1):18401. doi: 10.1038/s41598-019-54986-2.
2
Heterotopic ossification: radiological and pathological review.异位骨化：影像学与病理学综述
Radiol Oncol. 2019 Sep 24;53(3):275-284. doi: 10.2478/raon-2019-0039.
3
Macrodystrophia Lipomatosa: A Single Large Radiological Study of a Rare Entity.巨脂性营养不良：一项针对罕见病症的大型影像学研究
J Clin Imaging Sci. 2019 Feb 27;9:4. doi: 10.25259/JCIS-9-4. eCollection 2019.
4
Heterotopic Ossification: A Comprehensive Review.异位骨化：全面综述
JBMR Plus. 2019 Feb 27;3(4):e10172. doi: 10.1002/jbm4.10172. eCollection 2019 Apr.
5
The imaging of osteomyelitis.骨髓炎的影像学检查
Quant Imaging Med Surg. 2016 Apr;6(2):184-98. doi: 10.21037/qims.2016.04.01.
6
Heterotopic ossification mimicking infection in patients with traumatic spinal cord injury.创伤性脊髓损伤患者中模仿感染的异位骨化
Technol Health Care. 2016;24(1):87-91. doi: 10.3233/THC-151070.
7
Somatic gain-of-function mutations in PIK3CA in patients with macrodactyly.肢端肥大症患者中 PIK3CA 的体细胞获得性功能突变。
Hum Mol Genet. 2013 Feb 1;22(3):444-51. doi: 10.1093/hmg/dds440. Epub 2012 Oct 24.
8
Heterotrophic ossification in a patient suspected of having osteomyelitis: additional value of SPECT/CT.疑似骨髓炎患者的异位骨化：SPECT/CT 的附加价值。
Clin Nucl Med. 2012 Feb;37(2):170-1. doi: 10.1097/RLU.0b013e31823e9ac0.
9
Macrodystrophia lipomatosa: four case reports.巨脂性肌营养不良症：四例报告。
Ital J Pediatr. 2010 Oct 22;36:69. doi: 10.1186/1824-7288-36-69.
10
II. Ossifying Haematoma.二、骨化性血肿
Ann Surg. 1893 Jul;18(1):8-17. doi: 10.1097/00000658-189307000-00002.