Fang Yan-Ping, Huang Yu-Ting, Chen Dian, Kan Yu, Wang Jin-Wei, Kang Xiao-Ling, Wang Di-Yi, Liao Jun, Jing Xiang-Hong
School of Acupuncture and Moxibustion, Fujian University of TCM, Fuzhou 350122, China.
School of Acupuncture and Moxibustion, Fujian University of TCM, Fuzhou 350122, China; 2Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, Beijing 100700.
Zhongguo Zhen Jiu. 2021 Jun 12;41(6):691-8. doi: 10.13703/j.0255-2930.20200411-0004.
To review systematically the effectiveness and safety of (Chinese massage)in treatment of functional constipation.
The articles on functional constipation treated with were collected by computer retrieval from 7 databases from the date of establishment to March 28, 2020, including Chinese biomedical literature database (SinoMed), China journal full-text database (CNKI), full-text database of Wanfang academic journals (Wanfang), VIP Chinese science and technology journal database(VIP), PubMed, Dutch medical literature database (EMbase) and the Cochrane Library. After data extraction and quality evaluation of the included articles, Meta analysis was conducted with RevMan5.3 software.
A total of 16 articles were included, with 1424 cases involved. Meta analysis results showed: ①The total effective rate in the treatment group was higher than that in the control group =1.28, 95%: 1.16-1.42, <0.000 01. ②The effective rate for the symptoms of functional constipation in traditional Chinese medicine in the treatment group was higher than that in the control group (=1.38, 95% :1.25-1.52, =6.31, <0.000 01). ③Adverse reactions in the treatment group in the treatment of functional constipation were less than those in the control group (=0.10, 95%: 0.02-0.49, =2.81, =0.005).④The effective rate of functional constipation treated on the base of syndrome differentiation in the treatment group was higher than that of the control group (=1.50, 95%: 1.08-2.10, =2.39, =0.02).⑤The improvements in fecal characteristics, defecation time and defecation frequency of the patients with functional constipation in the treatment group were better than those in the control group (<0.05).
therapy presents a certain advantages on its curative effect on functional constipation, has less adverse reactions and relieves the relevant symptoms of functional constipation. But more randomized controlled trials with high quality and large sample are required to provide further verification of its effect.
系统评价推拿治疗功能性便秘的有效性和安全性。
通过计算机检索中国生物医学文献数据库（SinoMed）、中国期刊全文数据库（CNKI）、万方学术期刊全文数据库（万方）、维普中文科技期刊数据库（VIP）、PubMed、荷兰医学文献数据库（EMbase）和考克兰图书馆7个数据库，收集自建库至2020年3月28日发表的关于推拿治疗功能性便秘的文献。对纳入文献进行数据提取和质量评价后，采用RevMan5.3软件进行Meta分析。
共纳入16篇文献，涉及1424例患者。Meta分析结果显示：①治疗组总有效率高于对照组（RR=1.28，95%CI：1.16-1.42，P<0.000 01）。②治疗组中医功能性便秘症状有效率高于对照组（RR=1.38，95%CI：1.25-1.52，Z=6.31，P<0.000 01）。③治疗组治疗功能性便秘的不良反应少于对照组（RR=0.10，95%CI：0.02-0.49，Z=2.81，P=0.005）。④治疗组辨证论治功能性便秘的有效率高于对照组（RR=1.50，95%CI：1.08-2.10，Z=2.39，P=0.02）。⑤治疗组功能性便秘患者的粪便性状、排便时间和排便频率改善情况优于对照组（P<0.05）。
推拿治疗功能性便秘在疗效方面具有一定优势，不良反应较少，能缓解功能性便秘相关症状。但需要更多高质量、大样本的随机对照试验进一步验证其疗效。
