Young P S, Smith D D, Walsingham B
Med J Aust. 1977 Oct 8;2(15):497-9. doi: 10.5694/j.1326-5377.1977.tb117755.x.
A study of 866 vaginal swabs from non-pregnant women showed that 167 (19.3%) contained Group B beta-haemolytic streptococci, with a predominance of Types 3 (31.4%) and Ib (25.2%). The incidence of severe neonatal infections due to Group B streptococci during a 3 1/2 year period at The Prince of Wales Hospital was examined, and a study was made of the distribution of serotypes and associated clinical features (including prematurity and abnormal deliveries) in 16 neonates with septicaemia and/or meningitis admitted to the Royal Alexandra Hospital for Children, and the Paediatric Department of The Prince of Wales Hospital. From this study it was concluded that prophylactic antibiotic therapy should be administered to neonates with evidence of Group B streptococcal colonization of the throat, umbilicus, or gut, when there is also evidence of prematurity, prolonged interval between membrane rupture and delivery, or other associated obstetric complications.
一项针对866名非孕妇阴道拭子的研究表明，167份（19.3%）含有B族β溶血性链球菌，其中以3型（31.4%）和Ib型（25.2%）为主。研究了威尔士亲王医院在3年半时间内由B族链球菌引起的严重新生儿感染的发生率，并对皇家亚历山德拉儿童医院和威尔士亲王医院儿科收治的16例患败血症和/或脑膜炎的新生儿的血清型分布及相关临床特征（包括早产和异常分娩）进行了研究。从这项研究得出的结论是，当有证据表明新生儿存在B族链球菌在咽喉、脐部或肠道定植，同时又有早产、胎膜破裂至分娩间隔时间延长或其他相关产科并发症的证据时，应给予预防性抗生素治疗。
