Milligan A, Graham-Brown R A, Sarkany I, Baker H
Department of Dermatology, Leicester Royal Infirmary, London, U.K.
Br J Dermatol. 1988 Jul;119(1):63-6. doi: 10.1111/j.1365-2133.1988.tb07102.x.
Four patients with erythropoietic protoporphyria (EPP) are reported, in whom oral iron produced clear-cut clinical and biochemical deterioration. This suggests that there are two biochemically and genetically distinct sub-groups of EPP patients distinguished by their dramatically different response to oral iron.