University of California, Los Angeles, United States.
University of California, Los Angeles, United States.
Neurosci Biobehav Rev. 2021 Aug;127:795-807. doi: 10.1016/j.neubiorev.2021.05.024. Epub 2021 Jun 2.
The study of memory is commonly associated with neuroscience, aging, education, and eyewitness testimony. Here we discuss how eating behavior is also heavily intertwined-and yet considerably understudied in its relation to memory processes. Both are influenced by similar neuroendocrine signals (e.g., leptin and ghrelin) and are dependent on hippocampal functions. While learning processes have long been implicated in influencing eating behavior, recent research has shown how memory of recent eating modulates future consumption. In humans, obesity is associated with impaired memory performance, and in rodents, dietary-induced obesity causes rapid decrements to memory. Lesions to the hippocampus disrupt memory but also induce obesity, highlighting a cyclic relationship between obesity and memory impairment. Enhancing memory of eating has been shown to reduce future eating and yet, little is known about what influences memory of eating or how memory of eating differs from memory for other behaviors. We discuss recent advancements in these areas and highlight fruitful research pursuits afforded by combining the study of memory with the study of eating behavior.
记忆研究通常与神经科学、衰老、教育和证人证词有关。在这里,我们讨论了饮食行为如何与记忆过程密切相关,但却被严重低估。这两者都受到类似的神经内分泌信号(例如,瘦素和胃饥饿素)的影响,并依赖于海马体的功能。虽然学习过程长期以来一直被认为会影响饮食行为,但最近的研究表明,最近的饮食记忆如何调节未来的消费。在人类中,肥胖与记忆表现受损有关,而在啮齿动物中,饮食诱导的肥胖会导致记忆迅速下降。海马体损伤会破坏记忆,但也会导致肥胖,突出了肥胖和记忆障碍之间的循环关系。增加对饮食的记忆已被证明可以减少未来的饮食,但对于影响饮食记忆的因素以及饮食记忆与其他行为记忆的区别知之甚少。我们讨论了这些领域的最新进展,并强调了通过将记忆研究与饮食行为研究相结合而获得的富有成效的研究追求。