酿酒酵母中两个线粒体抗霉素A抗性位点的定位
Mapping of the two mitochondrial antimycin A resistance loci in Saccharomyces cerevisiae.
作者信息
Michaelis G, Pratje E
出版信息
Mol Gen Genet. 1977 Nov 4;156(1):79-85. doi: 10.1007/BF00272255.
PMID:340894
Abstract
Retention or loss of the two new mitochondrial antimycin A resistance loci AI and AII has been analyzed in a large number of stable cytoplasmic petite mutants. Using these deletion mutants it was possible to localize the two antimycin A resistance loci in the OI--OII region of mitochondrial DNA. The genetic loci are mapped in the following order: OII--AI--AII--cobl--OI. The mapping relationship of mutants resistant to antimycin A or funiculosin to various cob mutants is described.
摘要
在大量稳定的细胞质小菌落突变体中，对两个新的线粒体抗霉素A抗性位点AI和AII的保留或缺失情况进行了分析。利用这些缺失突变体，有可能将两个抗霉素A抗性位点定位在线粒体DNA的OI - OII区域。这些基因位点按以下顺序定位：OII - AI - AII - cobl - OI。描述了对抗霉素A或链丝菌素耐药的突变体与各种cob突变体之间的定位关系。
Zotero 插件